2002-2013年上海市浦东新区居民前列腺癌发病死亡趋势分析

发布时间：2018-12-21 19:26

【摘要】：目的分析上海市浦东新区男性居民2002-2013年前列腺癌发病和死亡情况,并预测其发展趋势,为前列腺癌防治策略提供参考。方法以2002-2013年上海市浦东新区常住户籍居民为研究对象,按1985年世界标准人口和1982年中国标准人口计算前列腺癌标化率(age-standardized rate,ASR),包括发病率和死亡率,并应用Join-point regression program分析率值的年均变化百分比(annual percent change,APC)进行趋势分析。结果 2002-2013年浦东新区新发前列腺癌3 235例,世界标化发病率为10.20/10万人年,中标率为7.01/10万人年,逐年上升趋势明显,APC=6.14%,z=9.49,P0.001;45~59岁随年龄增加呈上升趋势,APC=54.66%,z=2.73,P=0.02;60岁上升趋势明显,APC=10.77%,z=3.79,P=0.003;85岁达到最高峰(244.99/10万人年)。2002-2013年前列腺癌死亡1 570例,世界标化死亡率为4.66/10万人年,中标率为2.70/10万人年,逐年显著上升,APC=5.99%,z=4.42,P=0.001;40~69岁随年龄增加呈上升趋势,APC=27.12%,z=11.28,P0.001;70岁上升趋势明显,APC=16.89%,z=5.19,P0.001;85岁达到最高峰(322.31/10万人年)。结论浦东新区前列腺癌发病率和死亡率近年来逐年呈明显上升趋势,相关部门应积极开展前列腺癌病因学研究并应用早期诊断技术以降低其发病率和死亡率。
[Abstract]:Objective to analyze the incidence and death of prostate cancer in male residents of Pudong New District of Shanghai from 2002 to 2013, and to predict its development trend, and to provide reference for the prevention and treatment of prostate cancer. Methods the standard rate of prostate cancer (age-standardized rate,ASR), including morbidity and mortality, was calculated according to the world standard population of 1985 and the standard population of China in 1982 from 2002 to 2013. The average annual variation percentage of Join-point regression program analysis rate (annual percent change,APC) was used to analyze the trend. Results from 2002 to 2013, 3,235 new cases of prostate cancer were reported in Pudong New area. The world standardized incidence rate was 10.20% / 100,000 person-years, and the winning rate was 7.01% -100,000 person-years. The trend of increase was obvious year by year. APC=6.14%,z=9.49,P0.001; The age of 45 to 59 years showed an upward trend with the increase of age, while that of APC=54.66%,z=2.73,P=0.02;60 years showed an obvious upward trend. APC=10.77%,z=3.79,P=0.003;. From 2002 to 2013, there were 1 570 prostate cancer deaths, the world standardized mortality rate was 46. 66%-10, 000 person-years, the winning rate was 27. 0 / 100, 000 person-years, and the APC=5.99%, increased significantly year by year. ZZN 4.42, P0. 001; The age of 4069 years showed an upward trend with the increase of age, while the trend of APC=27.12%,z=11.28,P0.001;70 years was obvious, and the APC=16.89%,z=5.19,P0.001;85 year reached its highest peak (322.31 / 100000 person years). Conclusion the incidence and mortality of prostate cancer in Pudong New area have been increasing year by year. The etiology of prostate cancer should be studied actively and the early diagnosis technique should be used to reduce the morbidity and mortality of prostate cancer.
【作者单位】：上海市浦东新区疾病预防控制中心肿瘤伤害防治与生命统计科;
【基金】：上海市浦东新区卫生系统重点专科(病)建设项目(PWZz2013-15)
【分类号】：R737.25

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