绝经后女性不同Singh指数骨扫描电镜特点

发布时间：2017-12-28 20:27

本文关键词：绝经后女性不同Singh指数骨扫描电镜特点　出处：《中国老年学杂志》2016年04期 　论文类型：期刊论文

【摘要】：目的观察绝经后女性不同Singh指数股骨头骨小梁结构及骨超微结构情况。方法取股骨颈骨折、粗隆间骨折绝经后女性患者行假体置换患者股骨头标本33份,将33份标本采用低真空扫描电镜观察股骨头主要承重区骨小梁和骨超微结构;拍摄术前健侧X线片进行Singh指数分级。结果不同Singh指数分级扫描电镜下呈现出明显的差异,对于Singh指数6级,骨小梁结构完整显示清晰,高倍镜下骨胶原纤维排列紧密为特征;Singh指数5级和4级镜下辨别困难,共同特点为骨小梁变细,表面欠光滑,部分骨小梁出现断裂和缺失现象,骨胶原纤维出现卷曲,局部出现分散情况,但这对于6级和3级分辨清晰;Singh指数3级扫描电镜下骨小梁断裂、缺失情况普遍,骨胶原纤维断裂、排列散乱为其特征;Singh指数1级和2级分辨困难,表现为骨小梁结构破坏严重,骨胶原纤维出现大部分断裂、缺失情况。结论女性患者Singh指数可以大致反映骨结构的变化,了解骨质疏松情况,但因其主观因素影响,6级分法不能更加准确反映出骨结构,尤其是骨超微结构的具体变化。
[Abstract]:Objective To observe the structure and ultrastructure of the bone trabecular bone of the femur bone with different Singh index in postmenopausal women. Methods the femoral neck fracture, intertrochanteric fractures in postmenopausal women with prosthetic replacement in patients with femoral head specimens of 33 copies, 33 specimens with low vacuum scanning electron microscope observation of the main bearing area of the femoral head trabecular and bone ultrastructure; taken preoperative contralateral radiographs were graded index Singh. The results of different Singh index under the scanning electron microscope showed a significant difference, Singh index for 6, the trabecular structure complete clear display, high magnification of bone collagen fibers arranged closely to feature; Singh index 5 and 4 mirror to distinguish difficult, common characteristics for the bone surface was not smooth, part of Liang Bianxi. Trabecular bone fracture and the phenomenon of lacking collagen fiber appeared curl, the emergence of local dispersion, but for the 6 level and 3 level resolution clear; Level 3 Singh index under scanning electron microscopy, trabecular bone fracture, loss of common faults, the collagenous fibers were scattered as its features; Singh index of grade 1 and 2 the difficulty level resolution, showed that the trabecular bone structure damaged seriously, most of the broken, loss of collagen fiber appeared. Conclusion the Singh index of female patients can reflect the change of bone structure and understand osteoporosis. However, because of its subjective factors, the 6 level method can not reflect the specific changes of bone structure, especially the ultrastructure of bone.
【作者单位】：承德医学院附属医院关节外科;承德县医院骨科;
【基金】：承德市科学技术研究与发展计划项目(20121045)
【分类号】：R580
【正文快照】： 绝经后女性Singh指数可以大致反映骨结构的变化,了解骨质疏松情况,但因其主观因素影响,6级分法不能更加准确反映出骨结构,尤其是骨超微结构的具体变化。1材料和方法1.1材料来源本实验标本均来自我院2009年11月至2013年10月收治股骨颈和转子间骨折女性患者行假体置换取下的股骨

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