老年内科住院患者2型糖尿病和慢性肾脏病的相关性

发布时间：2018-01-03 08:22

本文关键词：老年内科住院患者2型糖尿病和慢性肾脏病的相关性　出处：《中国老年学杂志》2016年07期 　论文类型：期刊论文

【摘要】：目的初步探讨老年内科住院患者2型糖尿病(T2DM)和慢性肾脏病(CKD)的相关性。方法对2013年上海市第八人民医院老年科住院的152例70岁以上患者资料进行回顾性分析。了解高血压、糖尿病病史,测定空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、血脂、肾功能等指标。采用肾脏病膳食改良试验(MDRD)公式计算肾小球滤过率(e GFR)。结果 1老年患者中CKD患病率高(35.53%),T2DM中更高(42.53%)。2DM组高血压患病率、甘油三酯(TG)、血尿素、肌酐、尿酸均高于非DM组(P0.05),高密度脂蛋白胆固醇(HDL-C)和MDRD公式计算的GFR低于非DM组(P0.01)。3逐步多元线性回归分析显示,高尿酸血症、年龄和Hb A1c为e GFR的危险因素。结论老年住院患者中T2DM的CKD患病率更高(42.53%vs 35.53%),T2DM中存在的代谢紊乱可能是CKD的加重因素,GFR下降的危险因素除老龄化和血糖控制不佳外,高尿酸血症也是重要危险因素。
[Abstract]:Objective to investigate the elderly hospitalized patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). The correlation method of Shanghai Eighth People's Hospital in 2013 152 cases of hospitalized elderly patients aged over 70 years were retrospectively analyzed. Understanding of hypertension, diabetes, fasting blood glucose (FBG), glycosylated hemoglobin (Hb A1c), blood lipid and renal function indices. Using the modification of diet in renal disease (MDRD) calculated glomerular filtration rate (E, GFR). The high prevalence rate of 1 elderly patients with CKD results (35.53%), higher T2DM (42.53%).2DM group, the prevalence rate of hypertension, triglyceride (TG), blood urea, creatinine and uric acid were higher than that of the non DM group (P0.05), high density lipoprotein cholesterol (HDL-C) and MDRD formula GFR lower than non DM group (P0.01).3 stepwise multiple linear regression analysis showed that hyperuricemia, age and risk factors for e Hb A1c GFR. Conclusion in hospitalized elderly patients The prevalence of CKD in T2DM was higher (42.53%vs 35.53%), and the metabolic disorder in T2DM may be an aggravating factor of CKD. The risk factors for GFR decline were not only aging but also poor glycemic control. Hyperuricemia is also an important risk factor.

【作者单位】：上海市第八人民医院;
【分类号】：R587.2
【正文快照】： 中国慢性肾脏病(CKD)流行病学调查〔1,2〕结果显示,我国成年人CKD的患病率达到10.8%,接近欧美国家的成人CKD患病率(10.2%~13%)〔3,4〕。我国60岁以上老年人群的患病率更是高达32%,而患者对自身病情的知晓率仅为12.5%。糖尿病(DM)是CKD的传统危险因素,其患病率也在持续上升,目

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