2型糖尿病患者腓肠肌痉挛与踝肱指数关系研究

发布时间：2018-01-17 23:15

本文关键词：2型糖尿病患者腓肠肌痉挛与踝肱指数关系研究　出处：《上海交通大学学报(医学版)》2016年10期 　论文类型：期刊论文

【摘要】：目的·探讨2型糖尿病患者腓肠肌痉挛与踝肱指数(ABI)的关系。方法·选择2型糖尿病患者300例,根据有无腓肠肌痉挛分为阳性组(n=70)和阴性组(n=230),分别检测各组血糖、血脂、血电解质、ABI和下肢血管彩色超声等,进行单一因素方差分析和χ2检验,采用多因素非条件Logistic回归分析2型糖尿病患者腓肠肌痉挛的危险因素。结果·12型糖尿病腓肠肌痉挛阳性组的空腹血糖(FBG)、三酰甘油(TAG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、吸烟率、下肢动脉硬化和下肢动脉斑块的发生率显著高于阴性组(P0.05)。ABI在腓肠肌痉挛阳性组显著低于阴性组。2ABI0.9的2型糖尿病患者的腓肠肌痉挛发生率显著高于ABI正常组和ABI1.3组。3低ABI、高血糖、高胆固醇血症、高低密度脂蛋白胆固醇血症、吸烟、下肢动脉硬化、下肢动脉斑块是2型糖尿病患者腓肠肌痉挛的危险因素,非痛性糖尿病神经病变不引起糖尿病患者腓肠肌痉挛发生率的增加。结论·2型糖尿病患者腓肠肌痉挛和下肢动脉病变、吸烟、高血糖、高血脂有关。2型糖尿病患者一旦出现腓肠肌痉挛,应行ABI检查了解有无下肢动脉病变。
[Abstract]:Objective: to investigate the relationship between gastrocnemius spasm and ankle-brachial index (ABI) in type 2 diabetes mellitus. Gastrocnemius spasm was divided into positive group (n = 70) and negative group (n = 230). Blood glucose, blood lipid, blood electrolyte ABI and lower extremity blood vessel color ultrasound were detected. Single factor analysis of variance and 蠂 2 test were performed. Multivariate Logistic regression analysis was used to analyze the risk factors of gastrocnemius spasm in type 2 diabetic patients. Triglyceride, total cholesterol, low density lipoprotein cholesterol, low density lipoprotein cholesterol, smoking rate. The incidence of arteriosclerosis and plaque in lower extremity was significantly higher than that in negative group (P0.05). The incidence of gastrocnemius spasm in positive gastrocnemius spasm group was significantly lower than that in type 2 diabetic patients with type 2 diabetes in negative group. 2ABI 0.9. The incidence of gastrocnemius spasm in patients with type 2 diabetes was significantly higher than that in normal ABI group and ABI1.3 group. Hyperglycemia, hypercholesterolemia, high and low density lipoprotein cholesterol, smoking, arteriosclerosis of lower extremity and arterial plaque of lower extremity were risk factors of gastrocnemius spasm in type 2 diabetes mellitus. Non-pain diabetic neuropathy did not increase the incidence of gastrocnemius spasm in diabetic patients. Conclusion 路type 2 diabetes mellitus patients with gastrocnemius spasm and lower extremity artery disease smoking and hyperglycemia. Once gastrocnemius spasm occurs in type 2 diabetic patients with hyperlipidemia, ABI examination should be performed to find out whether there are arterial lesions in the lower extremity.
【作者单位】：福建医科大学附属龙岩第一医院内分泌科;上海交通大学医学院附属仁济医院神经外科;
【基金】：福建省卫生计生委青年科研课题(2014-1-94)~~
【分类号】：R587.1
【正文快照】： 腓肠肌痉挛,俗称“小腿抽筋”,是痛性痉挛中最常见的一种,其特点是腓肠肌突然发作的强直性痛性痉挛,牵掣、痛如扭转,可持续数十秒至数分钟或更久。腓肠肌痉挛的原因有寒冷刺激、过度疲劳、缺钙和动脉硬化等,2型糖尿病患者因存在缺钙、动脉硬化、下肢缺血等原因,导致腓肠肌痉

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