ALA光动力联合中药保留灌肠治疗AIDS合并肛管尖锐湿疣临床观察

发布时间：2018-01-29 22:24

本文关键词： 艾滋病尖锐湿疣盐酸氨基酮戊酸外用散光动力中药保留灌肠　出处：《中国艾滋病性病》2017年01期 　论文类型：期刊论文

【摘要】：目的观察盐酸氨基酮戊酸外用散(ALA)光动力联合中药保留灌肠治疗,对艾滋病(AIDS)合并肛管尖锐湿疣患者的疗效。方法治疗组给予ALA光动力联合中药保留灌肠治疗,对照组给予ALA光动力治疗,比较两组的治疗有效率、复发率及不良反应发生率。结果 42例均为皮肤科门诊及艾滋病抗病毒治疗门诊收治的患者,随机分为2组,治疗组21例,对照组21例,两组患者在年龄、性别、病程、基础治疗等方面差异无统计学意义(P0.05)。疗程结束后,治疗组有效率100%(21/21),对照组有效率95.23%(20/21),两组有效率比较差异无统计学意义(P0.05);治疗组复发率14.3%,对照组复发率42.9%,治疗组复发率比对照组显著降低(P0.05);治疗组不良反应发生率19.0%,对照组不良反应发生率57.1%,治疗组不良反应发生率较对照组显著降低(P0.05)。结论 ALA光动力联合中药保留灌肠治疗艾滋病合并肛管尖锐湿疣患者,其复发率、不良反应发生率低,优于单纯ALA光动力治疗。
[Abstract]:Objective to observe the photodynamic therapy of aminolevulinic acid hydrochloride (ALAA) combined with traditional Chinese medicine (TCM) retention enema. Methods the treatment group was treated with ALA photodynamic therapy combined with traditional Chinese medicine retention enema, and the control group was treated with ALA photodynamic therapy. Results 42 cases of dermatological outpatient and AIDS antiviral treatment were randomly divided into two groups: treatment group (n = 21) and treatment group (n = 21). There was no significant difference in age, sex, course of disease and basic treatment between the two groups (P 0.05). After the course of treatment, the effective rate of the treatment group was 100 / 21 / 21). In the control group, the effective rate was 95.23% and 20 / 21%, and there was no significant difference in the effective rate between the two groups (P 0.05). The recurrence rate in the treatment group was 14.3cm, and the recurrence rate in the control group was 42.9%. The recurrence rate in the treatment group was significantly lower than that in the control group (P 0.05). The incidence of adverse reactions was 19.0 in the treatment group and 57.1% in the control group. The incidence of adverse reactions in the treatment group was significantly lower than that in the control group. Conclusion ALA photodynamic therapy combined with traditional Chinese medicine retention enema for the treatment of AIDS patients with anal condyloma acuminatum, its recurrence rate. The incidence of adverse reactions was low and superior to ALA photodynamic therapy alone.
【作者单位】：武汉市第八医院皮肤科;
【分类号】：R512.91;R752.53
【正文快照】： 尖锐湿疣是由人乳头瘤病毒(HPV)感染引起的,以发生在外生殖器、肛周为主的良性增生性传染病[1]。近年来武汉市第八医院皮肤性病科、艾滋病抗病毒治疗科收治的艾滋病合并肛管内尖锐湿疣的病人明显增多。分析原因为近年来随着男男性行为者(MSM)人数增多,其无保护性肛交、群交及

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