全自动换血疗法在急性有机磷农药中毒中间综合征中的应用研究

发布时间：2018-01-30 15:52

本文关键词： 胆碱酯酶类有机磷农药中毒全自动外周动静脉同步换血　出处：《重庆医学》2017年22期 　论文类型：期刊论文

【摘要】：目的探讨全自动换血疗法治疗急性有机磷农药中毒中间综合征的疗效及其安全性。方法分析30例采用全自动换血疗法的急性有机磷农药中毒中间综合征患者换血前后的生命体征、胆碱酯酶、pH值、血常规变化等生化指标变化情况。结果换血前后患者的呼吸、心率、血压无统计学意义(P0.05);换血前后患者的血红蛋白、白细胞、血小板差异无统计学意义(P0.05);换血前后患者的K、Na、Ca、pH、血糖差异无统计学意义(P0.05)、而胆碱酯酶换血前后显著降低(P0.05);所有中毒症状明显改善,未见其他并发症。结论全自动换血疗法能安全、快速降低有机磷农药中毒中间综合征患者胆碱酯酶含量,操作简单。
[Abstract]:Objective to investigate the efficacy and safety of automatic exchange of blood therapy in the treatment of intermediate syndrome of acute organophosphorus pesticide poisoning. Methods 30 cases of intermediate syndrome of acute organophosphorus pesticide poisoning were analyzed. Vital signs before and after blood. Results there was no significant difference in respiration, heart rate and blood pressure between patients before and after blood exchange (P 0.05). There was no significant difference in hemoglobin, white blood cells and platelets before and after exchange of blood. There was no significant difference in blood glucose between the two groups before and after blood exchange (P 0.05), but cholinesterase significantly decreased P0.05A before and after hemodialysis. Conclusion automatic blood exchange therapy is safe and rapid to reduce cholinesterase content in patients with intermediate syndrome caused by organophosphorus pesticide poisoning.
【作者单位】：广西壮族自治区人民医院急诊科重症监护病房;
【基金】：广西壮族自治区卫生和计划生育委员会科技研究计划课题(Z2013400)
【分类号】：R595.4
【正文快照】： 有机磷农药中毒在临床上很常见,出现有机磷农药中毒中间综合征(IMS)的死亡率高[1-2]。换血疗法已经成为此类患者的辅助治疗手段之一[3]。目前,该疗法的方式主要有静-静脉换血及动-静脉换血两种方式,应用于有机磷农药中毒的解救中主要以手控操作为主,这样的方式消耗大量的人力

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