甲状腺功能亢进症合并急性冠状动脉综合征的影响因素分析

发布时间：2018-01-31 01:53

本文关键词： 甲状腺功能亢进症急性冠状动脉综合征危险因素　出处：《中国现代医学杂志》2017年13期 　论文类型：期刊论文

【摘要】：目的探讨甲状腺功能亢进症(甲亢)合并急性冠状动脉综合征(ACS)的危险因素。方法选取2010年1月-2016年12月的甲亢合并ACS患者及单纯甲亢患者。分别设为ACS组及对照组,收集患者的性别、年龄、吸烟、生化及冠状动脉造影等临床资料,进行比较及危险因素分析。结果 ACS组甲亢病程较对照组长,甲亢未控制率及平均年龄均较对照组高,且男性患者所占比例亦较对照组高;ACS组游离三碘甲状腺原氨酸(FT3)、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)及脑钠肽(BNP)水平高于对照组;Logistic回归分析发现,年龄、性别、FT3、高血糖及较长的甲亢病程均为甲亢合并ACS患者的危险因素。结论多种因素可影响甲亢患者ACS的发生。
[Abstract]:Objective to investigate acute coronary syndrome (ACS) in hyperthyroidism (hyperthyroidism). Methods from January 2010 to December 2016, patients with hyperthyroidism complicated with ACS and patients with simple hyperthyroidism were divided into ACS group and control group. The clinical data of sex, age, smoking, biochemistry and coronary angiography were collected, and the risk factors were analyzed. Results the course of hyperthyroidism in ACS group was longer than that in control group. The uncontrolled rate and average age of hyperthyroidism were higher than those of the control group, and the proportion of male patients was higher than that of the control group. The levels of free triiodothyronine (FT _ 3N), fasting blood glucose (FBG), HbA1c (glycosylated hemoglobin) and brain natriuretic peptide (BNP) in ACS group were higher than those in control group. Logistic regression analysis showed that age and sex were FT3. Hyperglycemia and long course of hyperthyroidism were the risk factors of hyperthyroidism with ACS. Conclusion many factors may influence the occurrence of ACS in hyperthyroidism patients.
【作者单位】：西南医科大学临床医学院;四川省医学科学院(四川省人民医院全科医学中心);
【分类号】：R541.4;R581.1
【正文快照】： 甲状腺功能亢进症(甲亢)是甲状腺腺体本身产生甲状腺激素过多而引起的甲状腺毒症,可导致全身多器官受累[1-2]。甲状腺功能亢进型心脏病,主要包括心律失常、冠心病、心脏增大和心力衰竭[3]。急性表1各组患者的一般临床资料比较(n=22)组别年龄/(岁,x±s)男/女/例甲亢病程/月甲亢

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