糖尿病足患者腓神经传导速度及相关因素分析

发布时间：2018-02-09 08:41

本文关键词： 糖尿病足肌电图腓神经　出处：《安徽医科大学学报》2017年05期 　论文类型：期刊论文

【摘要】：目的分析糖尿病足溃疡患者和未发生糖尿病足的2型糖尿病患者的肌电图腓神经传导速度的差异及其影响因素。方法收集54例住院糖尿病足患者和54例住院不伴有糖尿病足的2型糖尿病患者的资料,回顾性分析这108例患者的临床资料,研究糖尿病足溃疡患者和未发生糖尿病足的2型糖尿病患者的肌电图腓神经传导速度的差异及其影响因素。结果糖尿病足组与对照组相比,双下肢肌电图腓神经传导速度较慢,差异有统计学意义(P0.05)。两组患者在受教育程度、白细胞计数、中性粒细胞比例、血红蛋白、白蛋白、踝肱指数(ABI)方面差异有统计学意义(P0.05)。腓神经感觉神经传导速度与糖化血红蛋白、白细胞计数、中性粒细胞比例呈负相关性(P0.05);与空腹C肽水平、血红蛋白、白蛋白及ABI呈正相关性(P0.05)。腓神经运动神经传导速度与吸烟时间、糖化血红蛋白、中性粒细胞比例呈负相关性(P0.05);与血红蛋白、白蛋白水平呈正相关性(P0.05)。结论糖尿病周围神经病变是导致糖尿病足溃疡的重要危险因素。血糖控制差、感染、吸烟、胰岛功能差、贫血、低蛋白血症及下肢血供差均可能是糖尿病周围神经病变发生或发展的促进因素。因此,预防和治疗糖尿病足就应该注重血糖控制、积极抗感染、改善或保护患者胰岛功能、纠正贫血和低蛋白血症,同时需注重对患者进行糖尿病教育及足病知识教育。
[Abstract]:Objective to analyze the differences of electromyographic peroneal nerve conduction velocity between diabetic foot ulcer patients and type 2 diabetic patients without diabetic foot. Methods 54 patients with diabetic foot and 54 patients without diabetic foot were collected. Data on type 2 diabetic patients with diabetic foot, The clinical data of 108 patients with diabetic foot ulcers and type 2 diabetic patients without diabetic foot were analyzed retrospectively, and the difference of electromyography peroneal nerve conduction velocity and its influencing factors were studied. Results the diabetic foot group was compared with the control group. The lower extremity electromyography of peroneal nerve conduction velocity was slow, the difference was statistically significant (P 0.05). The two groups were educated, white blood cell count, neutrophil ratio, hemoglobin, albumin, There was a significant difference in ankle brachial index (ABI). There was a negative correlation between the conduction velocity of sensory nerve of peroneal nerve and glycosylated hemoglobin, white blood cell count, neutrophil ratio, and the level of fasting C-peptide, hemoglobin. There was a positive correlation between albumin and ABI. There was a negative correlation between peroneal nerve motor nerve conduction velocity and smoking time, glycosylated hemoglobin, neutrophilic granulocyte ratio. Conclusion Diabetic peripheral neuropathy is an important risk factor for diabetic foot ulcer. Hypoproteinemia and lower extremity blood supply may be the promotive factors for the occurrence or development of diabetic peripheral neuropathy. Therefore, the prevention and treatment of diabetic foot should pay attention to blood glucose control, actively anti-infection, improve or protect the pancreatic islet function of patients. To correct anemia and hypoproteinemia, attention should be paid to diabetes education and foot disease education.
【作者单位】：安徽医科大学第一附属医院内分泌科;
【基金】：安徽省卫生厅医学科研重点项目(编号:2010A008)
【分类号】：R587.2

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