维吾尔族内脏脂肪面积与尿酸及代谢综合征的相关性研究

发布时间：2018-02-21 07:35

本文关键词： 维吾尔族内脏脂肪面积血尿酸代谢综合征相关性　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:讨论乌鲁木齐市天山区维吾尔族内脏脂肪面积与血尿酸及代谢综合征之间的相关性。方法:研究采用多阶段分层整群随机抽样,在新疆乌鲁木齐市天山区中二道桥片区对1268名维吾尔族居民进行横断面调查。所有居民均测量收缩压(SBP)、舒张压(DBP)、腰围(WC),并检测空腹血糖(FPG)、血浆总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)及血尿酸(UA)水平。使用人体成分分析仪测量腹内脂肪面积(VFA)。根据检测结果分析内脏脂肪面积与尿酸及代谢综合征之间的相关性。结果:维吾尔族男女H-VFA组血尿酸水平明显高于L-VFA组(p0.01),内脏脂肪面积预测血尿酸的ROC曲线下面积为0.718;维吾尔族男女H-VFA组中MS的患病率明显高于L-VFA组(p0.01),内脏脂肪面积预测代谢综合征存在的ROC曲线下面积为0.858;维吾尔族男女内脏脂肪面积(VFA)与体质指数、体重、臀围、收缩压、舒张压、空腹血糖、2h血糖、糖化血红蛋白、甘油三酯、总胆固醇、低密度脂蛋白及尿酸呈正相关,与高密度脂蛋白呈负相关。结论:在维吾尔族中,内脏脂肪面积与血尿酸及代谢综合征密切相关。
[Abstract]:Objective: to study the correlation between visceral fat area, uric acid and metabolic syndrome in Uygur nationality in Tianshan area of Urumqi. A cross-sectional survey was conducted among 1268 Uygur residents in Zhongerdaoqiao District, Tianshan District, Urumqi City, Xinjiang. Systolic blood pressure (SBP), diastolic blood pressure (DBP), waist circumference (WCG), fasting blood glucose (FBG), plasma total cholesterol (TC), triglyceride (triglyceride) were measured in all residents. The levels of TGG, HDL, LDL and UAA were measured by body composition analyzer. The correlation between visceral fat area and uric acid and metabolic syndrome was analyzed based on the results. Results: the level of serum uric acid in H-VFA group was significantly higher than that in L-VFA group, and the area under ROC curve of visceral fat area in predicting serum uric acid was 0.718. The prevalence of MS in H-VFA group was significantly higher than that in L-VFA group and visceral fat. The area under the ROC curve was 0.858, the area of visceral fat in Uygur men and women was 0.858, the area of visceral fat and body mass index (BMI) of Uygur men and women. Body weight, hip circumference, systolic blood pressure, diastolic blood pressure, fasting blood glucose 2 h glucose, glycosylated hemoglobin, triglyceride, total cholesterol, low density lipoprotein and uric acid were positively correlated, and negatively correlated with high density lipoprotein. The area of visceral fat is closely related to serum uric acid and metabolic syndrome.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R589

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