冰黄药凝胶对糖尿病足溃疡创面疗效的研究

发布时间：2018-02-26 06:13

本文关键词： 冰黄药凝胶糖尿病足溃疡感染疗效　出处：《中华医院感染学杂志》2017年20期 　论文类型：期刊论文

【摘要】：目的探讨冰黄药凝胶对糖尿病足溃疡感染创面的治疗效果,为糖尿病足溃疡感染的临床治疗提供参考依据。方法选取2015年12月-2016年12月医院收治的糖尿病足溃疡感染的患者88例为研究对象,根据治疗方法分为研究组和对照组,各44例;对照组患者给予氯化钠、胰岛素和庆大霉素纱布敷贴,研究组患者给予冰黄药凝胶治疗;对两组感染病原菌、生化指标、溃疡面愈合指标和临床疗效进行观察。结果研究组感染患者共检出病原菌58株,对照组感染患者共检出57株病原菌,两组患者均以铜绿假单胞菌为主;研究组患者的各项生化指标水平与对照组差异无统计学意义;研究组患者的溃疡面愈合时间、溃疡面面积和创面闭合指数分别为(15.34±7.23)d、(2.06±0.34)cm~2和(97.45±3.13)%均显著优于对照组的(20.62±9.31)d、(4.01±2.65)cm~2和(82.53±6.11)%(P均0.05);研究组患者的总有效率为90.91%显著高于对照组72.73%,差异有统计学意义(P0.05)。结论冰黄药凝胶能有效促进糖尿病足患者溃疡创面的愈合,提高临床综合治疗效果。
[Abstract]:Objective to investigate the therapeutic effect of ice xanthate gel on diabetic foot ulcer infection wound. Methods from December 2015 to December 2016, 88 patients with diabetic foot ulcer infection were divided into study group (44 cases) and control group (44 cases). The patients in the control group were treated with sodium chloride, insulin and gentamicin gauze, and the patients in the study group were treated with ice xanthate gel. Results 58 strains of pathogenic bacteria were detected in the study group and 57 strains in the control group. The two groups were mainly Pseudomonas aeruginosa. There was no significant difference in biochemical indexes between the study group and the control group, and the ulcer healing time of the patients in the study group was not significantly different from that in the control group. The surface area of ulcer and wound closure index were 15.34 卤7.23g / cm ~ (-2) and 97.45 卤3.13%, respectively, which were significantly better than those of control group (20.62 卤9.31) (4.01 卤2.65) cm ~ (-1) and (82.53 卤6.11) P 0.05.The total effective rate of patients in study group was 90.91% significantly higher than that in control group (72.73), and the difference was statistically significant (P 0.05). To promote the healing of ulcer wounds in diabetic foot patients. To improve the effect of clinical comprehensive treatment.
【作者单位】：河北省中医院内分泌科;河北省中医院外科;河北省中医院肿瘤内科;河北省中医院护理部;河北省中医院急诊科;
【基金】：河北省中医药管理局科研计划基金资助项目(2014169)
【分类号】：R587.2

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