2型糖尿病人群肾功能异常影响因素分析

发布时间：2018-03-03 00:05

本文选题：糖尿病　切入点：型　出处：《中华疾病控制杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的了解在社区管理的2型糖尿病人群肾功能异常现状以及其影响因素。方法于2014年,在淮安市招募了9 413名前期已纳入基本公共卫生服务管理的2型糖尿病患者进行问卷调查、体格检查和生化指标检测,以肾小球滤过率作为主要评价指标。结果 2型糖尿病患者肾小球滤过率(estimated glomerular filtration rate,e GFR)的平均水平为91 ml/(min·1.73 m~2),eGFR60 ml/(min·1.73 m~2)达10.56%;不同性别、不同年龄人群间肾功能异常率差异有统计学意义(x~2=6.306,P=0.012;x~2=269.293,P0.001),男性低于女性,年龄越大肾功能越差。多元分析表明,糖尿病病程、低密度脂蛋白、总胆固醇、甘油三酯的升高、血糖没有控制及患高血压等是肾功能下降的主要危险因素。结论 2型糖尿病人群易罹患肾功能异常,在健康管理中要加以关注。控制好血糖、血压和血脂对延缓2型糖尿病人群肾脏功能进一步恶化有帮助。
[Abstract]:Objective to investigate the status of renal dysfunction and its influencing factors in type 2 diabetes mellitus (DM) in community management. Methods on 2014, In Huai'an City, 9 413 patients with type 2 diabetes who had been included in the management of basic public health services were recruited for questionnaire survey, physical examination and biochemical index examination. Results the mean level of glomerular filtration rate estimated by glomerular filtration rate (GFR) in type 2 diabetic patients was 91 ml/(min 路1.73 mGFR60 ml/(min 路1.73 mGFR60 ml/(min 路1.73 mGFR). The rate of abnormal renal function was significantly different among different age groups. There were significant differences in the rate of abnormal renal function among different age groups. There were significant differences in renal function between male and female. The higher the age, the worse the renal function. Multivariate analysis showed that the course of diabetes, low density lipoprotein (LDL), total cholesterol, triglyceride, and triglyceride increased. Blood glucose and hypertension are the main risk factors of renal function decline. Conclusion Type 2 diabetes is prone to renal dysfunction, and should pay attention to it in health management. Blood pressure and blood lipids may help to delay the further deterioration of renal function in type 2 diabetes.
【作者单位】：淮安市疾病预防控制中心慢性病防制科;江苏省疾病预防控制中心慢性非传染病防制所;
【基金】：江苏省卫生厅医学创新团队科技项目(K201105) 2013年度江苏省第四期“333工程”科研资助立项项目(BRA2013107)
【分类号】：R587.1

【相似文献】