倒班年限与男性钢铁工人2型糖尿病患病率的剂量-反应关系

发布时间：2018-03-08 17:00

本文选题：男性钢铁工人　切入点：倒班年限　出处：《环境与职业医学》2017年06期 　论文类型：期刊论文

【摘要】：[目的]探讨倒班及倒班年限与男性钢铁工人2型糖尿病(T2DM)患病率的剂量-反应关系。[方法]采用现况研究的方法,调查2015年2月—2016年2月在某钢铁集团公司医院进行职业健康检查和健康体检的全部男性钢铁工人7 415人,用于分析7 209份问卷。收集资料包括男性钢铁工人人口学特征、生活方式、病史、家族史、身高、体重、职业史;采用多因素非条件logistic回归和限制性立方样条模型,分析男性钢铁工人倒班及倒班年限与T2DM之间的关联。[结果]男性钢铁工人T2DM患病率为16.5%。曾经倒班、现在倒班与T2DM患病有关,差别有统计学意义(P0.05),OR(95%CI)分别为:1.403(1.131~1.740),1.536(1.298~1.817)。调整一般因素和高温暴露等职业因素后,曾经倒班、现在倒班均与T2DM患病率有关联,且有统计学意义(P0.05),OR(95%CI)分别为:2.792(2.286~3.411)、2.546(2.076~3.124)。曾经倒班年限和T2DM有关联(χ~2=35.00,P0.000 1),呈非线性相关(χ~2=3.00,P=0.606 8);现在倒班年限和T2DM患病有关(χ~2=49.92,P0.000 1),呈非线性相关(χ~2=5.33,P=0.148 9)。[结论]倒班年限与男性钢铁工人T2DM患病有关,且呈非线性相关。
[Abstract]:[objective] to investigate the dose-response relationship between the duration of shift and shift and the prevalence of type 2 diabetes mellitus (T2DM) in male iron and steel workers. From February 2015 to February 2016, a total of 7 415 male steel workers who underwent occupational health examination and physical examination in a hospital of a certain iron and steel group were investigated and used to analyze 7 209 questionnaires. The data collected included demographic characteristics of male steel workers. Lifestyle, medical history, family history, height, weight, career history, multivariate conditional logistic regression and restricted cubic spline model, To analyze the relationship between the shift and the number of shifts and T2DM in male steel workers. [results] the prevalence rate of T2DM in male steel workers was 16.5.The shift shift was associated with T2DM disease. The difference was statistically significant (P 0.05): 1. 403 / 1.131 / 1.740 / 1.740 / 1. After adjusting for occupational factors such as general factors and exposure to high temperature, there was once shift shift, and now shift work is associated with the prevalence of T2DM. Moreover, there was a statistically significant correlation between the number of shift years and T2DM (蠂 23.00 P 0.0001g) (蠂 23.00P0.606 8C), which was 2.792 / 2.2863.4111.There was a nonlinear correlation between the number of years of shift work and T2DM (蠂 25.333P0.148) (蠂 23.00P0.606 8C); the current shift period was related to the prevalence of T2DM (蠂 29.92P 0.000), and there was a nonlinear correlation (蠂 25.333P0.148). [conclusion] the shift period is related to the prevalence of T2DM in male iron and steel workers (蠂 29.92P 0.148). [conclusion] T2DM in male steel workers is related to the shift period of working hours (蠂 23.00 P 0.606 8) (蠂 23.00 P 0.606 8). And it is nonlinear correlation.
【作者单位】：华北理工大学公共卫生学院河北省煤炭职业卫生与安全实验室;唐山钢铁集团有限责任公司医院;
【基金】：河北省科技支撑重大项目(编号:132777090) 河北省自然科学基金课题(编号:H2016209058) 国家重点研发计划:精准医学研究(编号:2016YFC0900605)
【分类号】：R587.1

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