晕动病前庭生理机制研究进展

发布时间：2018-03-08 17:55

本文选题：晕动病　切入点：前庭系统　出处：《第二军医大学学报》2016年08期 　论文类型：期刊论文

【摘要】：晕动病是在航空、航天、航海旅行及作业过程中,由异常加速度刺激引起的生理功能紊乱。已证实前庭系统作为运动感受和加速度信息加工的核心,对晕动病的诱发及自主神经症状的产生起重要作用。虽然晕动病的发生机制尚未完全阐明,但近年来在感觉冲突理论的生理基础、自主神经反射的神经机制等方面有了新的突破。本文综述了前庭-视觉-本体感觉信息整合、前庭-海马及前庭-皮质通路与运动信息加工、前庭-内脏反射通路及前庭递质系统与抗晕动病药物靶点等的研究进展,为促进新型晕动病防治手段的开发和应用提供借鉴。
[Abstract]:Motion sickness is a disorder of physiological function caused by abnormal acceleration during aviation, aerospace, navigation travel and operation. It has been proved that vestibular system is the core of motion perception and acceleration information processing. It plays an important role in the induction of motion sickness and the generation of autonomic nervous symptoms. Although the mechanism of motion sickness has not been fully elucidated, it has been the physiological basis of the theory of sensory conflict in recent years. New breakthroughs have been made in the neural mechanism of autonomic reflex. In this review, the vestibular visual proprioceptive information integration, vestibular hippocampal and vestibulo-cortical pathways and motor information processing are reviewed. The research progress of vestibule-visceral reflex pathway, vestibular transmitter system and drug targets of anti-motion sickness provides a reference for the development and application of new methods for the prevention and treatment of motion sickness.
【作者单位】：第二军医大学海军医学系航海特殊损伤防护教研室;
【基金】：国家自然科学基金(81272178) 军队后勤科研重点项目(BWS14J024)~~
【分类号】：R594.6

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