中山市男男性行为者HIV新发感染状况研究

发布时间：2018-03-23 01:18

本文选题：艾滋病病毒　切入点：新发感染　出处：《中国艾滋病性病》2017年06期 　论文类型：期刊论文

【摘要】：目的了解中山市男男性行为者(MSM)艾滋病新发感染情况及影响因素。方法利用自愿咨询检测门诊,在MSM中建立前瞻性队列,每隔半年随访纳入对象,收集其艾滋病病毒(HIV)检测结果及其他相关信息。结果 2014年4月至2016年4月共招募545名MSM,HIV新发感染16例,新发感染率为4.95/100人年。性角色为单纯插入者、单纯被插入者及双重角色者的新发感染率分别为0.87/100人年、7.17/100人年、7.26/100人年。COX回归多因素分析显示,性角色为单纯被插入者或双重角色者[调整风险比(HR_(调整))=3.019,95%可信区间(CI):1.013~8.993]、同性性伴数量3个以上(HR_(调整)=3.690,95%CI:1.069~12.734)、每次肛交时没坚持使用安全套者(HR_(调整)=2.324,95%CI:1.087~4.967)、自我评估感染风险低者(HR_(调整)=5.346,95%CI:1.652~17.296),更容易发生HIV新发感染。结论中山市MSM中HIV新发感染情况较严重,加强个性化干预和宣传教育可减少新发感染。
[Abstract]:Objective to investigate the prevalence and influencing factors of HIV / AIDS in MSM in Zhongshan City. Methods A prospective cohort was established in MSM by using voluntary counseling and testing, and the subjects were followed up every six months. Results from April 2014 to April 2016, a total of 545 new cases of MSMN HIV infection were recruited, with a new infection rate of 4.95 / 100 person-years. The rate of new infection was 0.87% / 100 person-year / 7.17% / 100 person-year / 7.26 / 100 person-year, respectively. Cox regression analysis showed that the rate of infection was 0.87% / 100 person-year and 7.26% / 100 person-year respectively. Sex role is simple insertee or dual role [adjustment risk ratio HRSARS (adjusted 3.019 95% CI / CI 1.0138.993], number of same-sex partners more than 3 HRs (adjust 3.690,95CI1.069: 12.734N), each anal sex does not insist on condom use (adjust 2.324995 CI: 1.0877.67), self-assess the risk of infection. The new HIV infection is more likely to occur in MSM in Zhongshan City. Conclusion the new infection of MSM in Zhongshan City is more serious. Individualized intervention and publicity and education can reduce new infection.
【作者单位】：中山市疾病预防控制中心;
【基金】：广东省医学科研基金指令性项目(C2015028)~~
【分类号】：R512.91

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