哮喘急性发作患者肺功能恢复时间的影响因素分析

发布时间：2018-04-01 09:44

本文选题：哮喘　切入点：呼吸功能试验　出处：《中国全科医学》2017年S2期

【摘要】：目的分析严重哮喘急性发作给予适当治疗后,引起肺功能恢复时间延长的相关因素。方法回顾性分析2013年12月—2016年7月新疆医科大学第一附属医院急诊科收治的51例哮喘急性发作患者。收集患者入院前及入院时有关临床指标,并运用统计学软件对数据进行分析。结果共有51例符合入组标准,男25例;平均年龄(52.2±18.9)岁;其中肥胖患者(BMI30 kg/m2)28例;既往有哮喘的患者27例;哮喘急性发作前规律使用糖皮质激素15例;伴有心脏病7例,伴有糖尿病12例,伴有过敏性鼻炎患者28例;入院后,需给予吸氧治疗29例,并发肺炎20例,并发呼吸道病毒感染18例;患者出院时肺功能优于入院时,差异有统计学意义(P0.001);51例患者的肺功能恢复时间范围较宽,为1~12 d,平均恢复时间(6.6±2.5)d;单因素分析显示哮喘急性发作前规律使用糖皮质激素(P0.001),入院期间并发呼吸道病毒性感染(P0.001),过敏性鼻炎(P=0.009)会导致肺功能恢复时间延长;多因素COX比例风险回归分析结果显示哮喘急性发作前规律使用糖皮质激素、入院时并发呼吸道病毒性感染与肺功能恢复时间延长具有相关性(P0.05)。结论哮喘急性发作后肺功能恢复的时间在不同患者之间是不同的,长期使用糖皮质激素以及并发呼吸道病毒感染是影响恢复时间的重要因素。
[Abstract]:Objective to analyze the effect of appropriate treatment on acute attack of severe asthma, Methods from December 2013 to July 2016, 51 patients with acute asthma attack admitted in the emergency department of the first affiliated hospital of Xinjiang medical university were retrospectively analyzed. The patients were collected before and after admission. Hospital clinical indicators, The data were analyzed by statistical software. Results A total of 51 cases (25 males, mean age 52.2 卤18.9) were found to be in accordance with the criteria of admission, including 30 cases of obesity, 27 cases of asthma, 30 cases of obesity and 27 cases of asthma. Regular use of glucocorticoid in 15 cases of asthma before acute attack, 7 cases of heart disease, 12 cases of diabetes mellitus and 28 cases of allergic rhinitis. After admission, 29 cases need oxygen therapy, 20 cases complicated with pneumonia. There were 18 patients complicated with respiratory tract virus infection, the pulmonary function of the patients was better than that of the patients at the time of admission, and the difference was statistically significant (P 0.001). The average recovery time was 6.6 卤2.5 days after 12 days, and the results of univariate analysis showed that preacute asthma with glucocorticoid P0.001, respiratory viral infection with P0.001 during admission and allergic rhinitis with P0.009 could prolong the recovery time of lung function. Multivariate COX proportional risk regression analysis showed that glucocorticoid was used regularly before acute attack of asthma. There was a correlation between respiratory tract viral infection and prolongation of pulmonary function recovery time on admission. Conclusion the time of pulmonary function recovery after acute attack of asthma is different among different patients. Long-term use of glucocorticoid and respiratory virus infection are important factors affecting recovery time.
【作者单位】：新疆医科大学第一附属医院急诊科;
【分类号】：R562.25

【相似文献】