阿托伐他汀对高血压合并高低密度脂蛋白胆固醇血症患者肾功能的影响

发布时间：2018-04-03 00:05

本文选题：高血压　切入点：高低密度脂蛋白胆固醇血症　出处：《中西医结合心血管病电子杂志》2017年29期

【摘要】：目的对阿托伐他汀对高血压合并高低密度脂蛋白胆固醇血症患者肾功能的影响进行分析研究,以供参考。方法选取我院2016年4月1日至2017年4月1日接受治疗的高血压合并高低密度脂蛋白胆固醇血症患者114例,根据随机分组原则,对参与研究患者分组,对照组患者使用苯磺酸氨氯地平进行治疗,研究组患者则在对照组患者的基础上,使用阿托伐他汀进行治疗,对两组患者的血压、高低密度脂蛋白胆固醇、尿微量白蛋白以及不良反应进行对比研究。结果研究组患者的血压情况、高低密度脂蛋白胆固醇以及尿微量白蛋白的改善情况明显优于对照组患者,且研究组患者的不良反应发生率明显低于对照组患者。认为差异有统计学意义(P0.05)。结论对高血压合并高低密度脂蛋白胆固醇血症患者使用阿托伐他汀进行治疗,可有效改善患者的血压情况、以及胆固醇各项指标,且对患者的肾功能有着极大的促进作用,进一步加强患者的治疗效果,具有较高的临床研究价值。
[Abstract]:Objective to study the effect of Atto vastatin on renal function in patients with hypertension and high density lipoprotein cholesterol.Methods 114 patients with hypertension and high density lipoprotein cholesterol were selected from April 1, 2016 to April 1, 2017 in our hospital. According to the principle of random grouping, the patients were divided into two groups.The patients in the control group were treated with amlodipine benzenesulfonic acid, while the patients in the study group were treated with Atto vastatin on the basis of the patients in the control group.Urinary microalbuminuria and adverse reactions were compared.Results the improvement of blood pressure, high and low density lipoprotein cholesterol and urinary microalbumin in the study group was significantly better than that in the control group, and the incidence of adverse reactions in the study group was significantly lower than that in the control group.The difference was statistically significant (P 0.05).Conclusion the use of Atto vastatin in patients with hypertension and high density lipoprotein cholesterol can effectively improve the blood pressure and cholesterol indexes, and can promote the renal function of the patients.Further strengthening the therapeutic effect of patients has high clinical research value.
【作者单位】：山东中医药大学附属医院检验科;
【分类号】：R544.1;R589.2

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