老年糖尿病患者颈动脉内中膜变化的超声表现

发布时间：2018-04-05 21:21

本文选题：糖尿病　切入点：颈动脉内中膜　出处：《中国老年学杂志》2017年22期

【摘要】：目的探讨老年糖尿病患者颈动脉内中膜厚度(IMT)变化的超声表现。方法 100例确诊为2型糖尿病的患者为病例组,同期选择100例无糖尿病史的健康人群作为对照组,受试者均行颈部血管彩超检查了解IMT变化情况。并分析老年糖尿病患者IMT变化的影响因素。结果病例组IMT、弹性条数(Ep)及硬化程度(β)均较对照组明显升高,且内膜增厚及斑块形成比例明显高于对照组(P0.05)。病例组软斑例数最高,其次为混合斑,硬斑最少,对照组硬斑例数最高,其次为软斑,混合斑数最少,差异有统计学意义(P0.05)。内中膜变化组年龄、糖尿病病程、糖化血红蛋白(Hb A1c)、空腹血糖(FPG)、低密度脂蛋白胆固醇(LDL-C)水平显著高于内中膜无变化组(P0.05)。年龄大,糖尿病病程长,Hb A1c、FPG水平升高是老年糖尿病患者发生颈动脉内中膜增厚或斑块形成的独立危险因素(P0.05)。结论老年糖尿病患者更容易出现颈动脉内中膜增厚或斑块形成,且软斑比例更高,高龄、糖尿病病程长、血糖控制不佳可以促进老年糖尿病患者IMT变化的发生。
[Abstract]:Objective to investigate the changes of carotid intima media thickness (IMT) in elderly diabetic patients.Methods 100 patients with type 2 diabetes were selected as case group and 100 healthy subjects without diabetes history as control group. All subjects were examined by color Doppler ultrasonography to find out the changes of IMT.The factors influencing the changes of IMT in elderly patients with diabetes were analyzed.Results the IMT, the number of elastic strips (Epp) and the degree of sclerosis (尾) in the case group were significantly higher than those in the control group, and the ratio of intimal thickening and plaque formation was significantly higher than that of the control group (P 0.05).The cases of soft spot in the case group were the highest, the mixed spot was the second, the hard spot was the least, in the control group, the number of the hard spot was the highest, the next was the soft spot, the number of the mixed spot was the least, the difference was statistically significant (P 0.05).The levels of age, course of diabetes, HbA1cN, fasting blood glucose, FPGN and LDL-C were significantly higher in the IMC group than in the IMC group (P 0.05).The high level of HbA1cFPG was an independent risk factor for carotid intima-media thickening or plaque formation in elderly patients with diabetes mellitus.Conclusion elderly patients with diabetes are more likely to develop carotid intima-media thickening or plaque formation, and the ratio of soft plaque is higher, advanced age, long course of diabetes, and poor blood glucose control can promote the occurrence of IMT changes in elderly patients with diabetes.
【作者单位】：海口市人民医院;温州医科大学附属舟山医院超声诊断科;
【分类号】：R587.2

【相似文献】