2型糖尿病患者甘油三酯与心肌梗死的相关性研究

发布时间：2018-04-09 20:49

本文选题：甘油三酯　切入点：心肌梗死　出处：《山西医科大学》2017年硕士论文

【摘要】：目的:分析2型糖尿病患者甘油三酯与心肌梗死的相关性,从心肌梗死危险因素角度进一步探讨与甘油三酯相关的心血管剩留风险。方法:回顾性分析从2016年2月至2016年7月该院收治的符合低密度脂蛋白胆固醇(LDL-C)2.0mmol/L的2型糖尿病患者218例,其中合并心肌梗死组112例,无心肌梗死组106例作为对照组,对两组间部分生化指标及病史进行研究。结果:2型糖尿病合并心肌梗死患者组饮酒史、高血压史、总胆固醇(TC)、甘油三酯(TG)、体重指数均高于对照组(p0.05),而高密度脂蛋白胆固醇(HDL-C)低于对照组(p0.05)差异有统计学意义;对心肌梗死采用多因素逐步Logistic回归分析,结果显示高血压、胆固醇、甘油三酯是心肌梗死的危险因素。结论:甘油三酯为心肌梗死的独立危险因素,在LDL-C正常的2型糖尿病患者这一类人群中,当合并有高甘油三酯血症时仍有发生心肌梗死的心血管剩留风险存在。
[Abstract]:Aim: to analyze the relationship between triglyceride and myocardial infarction in type 2 diabetes mellitus and to further explore the cardiovascular residual risk associated with triglyceride from the perspective of myocardial infarction risk factors.Methods: from February 2016 to July 2016, 218 patients with type 2 diabetes mellitus (LDL-CU 2.0 mmol / L) who were admitted to our hospital from February 2016 to July 2016 were analyzed retrospectively, including 112 patients with myocardial infarction and 106 patients without myocardial infarction as control group.Some biochemical indexes and history were studied between the two groups.Results there were significant differences in alcohol consumption history, hypertension history, total cholesterol TCU, triglyceride TGG, body mass index (BMI), and high density lipoprotein cholesterol (HDL-C) in patients with type 2 diabetes mellitus with myocardial infarction (P 0.05).Multivariate stepwise Logistic regression analysis was used for myocardial infarction. The results showed that hypertension, cholesterol and triglyceride were risk factors of myocardial infarction.Conclusion: triglyceride is an independent risk factor for myocardial infarction. In type 2 diabetes patients with normal LDL-C, there is still a risk of myocardial infarction in patients with hypertriglyceridemia.
【学位授予单位】：山西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R542.22;R587.1

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