全膝关节置换术结合中药治疗类风湿性关节炎的临床疗效观察

发布时间：2018-04-09 21:01

本文选题：膝关节　切入点：类风湿性关节炎　出处：《辽宁中医药大学》2015年硕士论文

【摘要】：目的:观察全膝关节置换术结合中药治疗类风湿性关节炎的临床疗效材料与方法:2012年1月到2014年12月于我院接受治疗的20例类风湿关节炎患者20膝,作为研究对象。其中男7例,女13例,年龄48~72岁,平均62.45岁;病程6~14年,平均9年;合并症:3例有糖尿病。随机分为试验组10例,对照组10例。两组所有选取患者根据病情均行全膝关节置换术治疗,常规治疗组(对照组)给予常规抗炎、消肿、预防血栓对症治疗,中西医结合组(试验组)除上述西医治疗外结合口服中药治疗。根据膝关节HSS评分系统进行评分,术后对两组患者膝关节的功能恢复进行系统性评价。本次研究所选取的患者,性别、年龄以及病程等比较,差异无统计学意义(P0.05),具有可比性。结果:试验组:优9膝,良1膝,可0膝,差0膝。膝关节HSS评分术前平均29.9分,术后2周随访平均得分88.3分,改善率为83.6%。优良率100%。对照组:优6膝,良2膝,可2膝,差0膝。膝关节HSS评分术前平均32.1分,术后2周随访平均得分83.4分,改善率为74.6%。优良率80%。试验组术后改善率优于对照组。差异有统计学意义(P0.5)。结论:全膝关节置换术结合中药治疗膝关节类风湿性关节炎是比较理想的方法,可以缓解关节疼痛,改善关节功能,调节全身免疫系统,提高生活质量。
[Abstract]:Objective: to observe the clinical efficacy of total knee arthroplasty combined with traditional Chinese medicine in the treatment of rheumatoid arthritis. From January 2012 to December 2014, 20 knees of 20 patients with rheumatoid arthritis were treated in our hospital.There were 7 males and 13 females with an average age of 62.45 years, a mean age of 62.45 years, a course of 6 ~ 14 years with an average of 9 years, and 3 cases with diabetes mellitus.They were randomly divided into trial group (n = 10) and control group (n = 10).All the selected patients in both groups were treated with total knee arthroplasty according to their condition. The routine treatment group (control group) was treated with routine anti-inflammatory, anti-swelling, and anti-thrombotic therapy.According to the HSS scoring system of knee joint, the function of knee joint in both groups was evaluated systematically after operation.There was no significant difference in patients, sex, age and course of disease in this study.Results: in the experimental group, 9 knees were excellent, 1 knee was good, 0 knees were fair, and 0 knees were poor.The average score of HSS score was 29.9 before operation and 88.3 after 2 weeks follow-up. The improvement rate was 83.6.The excellent and good rate is 100.The control group: excellent 6 knees, good 2 knees, fair 2 knees, poor 0 knees.The average score of HSS score was 32.1 points before operation and 83.4 points after 2 weeks follow-up. The improvement rate was 74.6%.The excellent and good rate is 80.The improvement rate of the experimental group was better than that of the control group.The difference was statistically significant (P 0.5).Conclusion: total knee arthroplasty combined with traditional Chinese medicine in the treatment of knee rheumatoid arthritis is an ideal method, which can relieve joint pain, improve joint function, regulate the whole body immune system and improve the quality of life.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R593.22

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