HbA1c水平与脑出血合并糖尿病患者迟发性脑水肿的相关性研究

发布时间：2018-04-17 09:48

本文选题：脑出血 + 糖尿病　；参考：《中国现代医学杂志》2017年10期

【摘要】：目的探讨HbA1c水平与脑出血合并糖尿病患者迟发性脑水肿的相关性。方法回顾性分析115例于唐山市工人医院神经外科住院的脑出血合并糖尿病患者。采用HPLC法检测HbA1c,根据HbA1c水平分为HbA1c7.0%组(A组)、7.0%~9.0%组(B组)和HbA1c9.0%组(C组),分析HbA1c水平对脑出血合并糖尿病患者迟发性脑水肿的影响。结果 3组迟发性脑水肿发生率差异有统计学意义(P0.05);脑出血合并糖尿病发生迟发性脑水肿患者水肿体积与HbA1c(r=0.814,P=0.000)、GCS评分(r=-0.780,P=0.000)、NIHSS评分(r=0.696,P=0.000)均相关;多元线性回归分析后,HbA1c与患者水肿体积仍相关(β=0.741,t=5.280,P=0.000)。结论 HbA1c水平与脑出血合并糖尿病患者迟发性脑水肿严重程度相关。
[Abstract]:Objective to investigate the correlation between HbA1c level and delayed cerebral edema in patients with cerebral hemorrhage and diabetes mellitus.Methods 115 cases of intracerebral hemorrhage complicated with diabetes mellitus in neurosurgery department of workers' hospital in Tangshan City were analyzed retrospectively.HbA1cwas detected by HPLC method. According to the level of HbA1c, HBA 1c7.0% group was divided into group A (7.0%) and group B (9.0%) and group C (9.0%). The effect of HbA1c level on delayed cerebral edema in patients with cerebral hemorrhage complicated with diabetes was analyzed.Results there were significant differences in the incidence of delayed cerebral edema among the three groups (P 0.05), and the volume of edema in patients with cerebral hemorrhage complicated with diabetes mellitus was correlated with the GCS score of HBA _ 1C _ (0.14) P _ (0.000) and the NIHSS score (r _ (0.696) P _ (0.000)).After multivariate linear regression analysis, HbA1c was still correlated with the edema volume (尾 -0.741t = 5.280).Conclusion the level of HbA1c is related to the severity of delayed cerebral edema in patients with cerebral hemorrhage and diabetes mellitus.
【作者单位】：河北省唐山市工人医院神经外科二科;河北省唐山市工人医院内分泌二科;河北省唐山市工人医院华北理工大学基础医学院组织胚胎学教研室;
【分类号】：R587.1;R743.34

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