糖尿病患者视网膜血管血氧饱和度变化研究

发布时间：2018-04-30 13:53

本文选题：糖尿病 + 血氧饱和度　；参考：《眼科新进展》2017年07期

【摘要】：目的观察糖尿病患者与健康人群视网膜血管血氧饱和度的差异。方法临床确诊为糖尿病的71例(71眼)患者和91名(91眼)健康者分别纳入糖尿病组和正常组。采用视网膜血管血氧饱和度测量仪检测两组受检者,并应用仪器配套软件分析距离视盘中心1.5~3.0个视盘直径的视网膜动脉、静脉血氧饱和度值。结果 71例糖尿病患者中,男性与女性、各个年龄段、不同糖尿病病程间比较,视网膜动脉、静脉及其各象限分支动脉、静脉的血氧饱和度差异均无统计学意义(均为P0.05)。糖尿病组视网膜动脉血氧饱和度较正常组显著升高(P=0.00);糖尿病组视网膜动脉各象限的血氧饱和度均较正常组高,其中颞上分支、颞下分支与正常组相比差异均有统计学意义(均为P0.05)。糖尿病组视网膜静脉血氧饱和度较正常组有升高的趋势,但差异无统计学意义(P0.05);糖尿病组视网膜静脉血氧饱和度颞上分支、颞下分支较正常组高,鼻下分支较正常组低,差异均有统计学意义(均为P0.05)。糖尿病组视网膜动静脉血氧饱和度差值较正常组显著升高(P=0.00)。结论糖尿病患者视网膜血管血氧饱和度与健康人群存在显著差异;糖尿病患者不同象限的血管血氧饱和度存在不同程度的改变,提示视网膜氧代谢异常程度在各象限的分布并不均匀。
[Abstract]:Objective to observe the difference of retinal blood vessel oxygen saturation between diabetic patients and healthy people. Methods 71 patients with diabetes mellitus (71 eyes) and 91 healthy subjects (91 eyes) were included in the diabetic group and the normal group respectively. Two groups of subjects were tested with retinal blood vessel oxygen saturation instrument, and the retinal artery with a diameter of 1.5 ~ 3.0 from the center of the optic disc was analyzed by using the instrument software, and the value of venous oxygen saturation was analyzed. Results in 71 patients with diabetes, there was no significant difference in blood oxygen saturation of retinal artery, vein and its branches and veins between male and female, between different age groups and different course of diabetes (all P 0.05). The blood oxygen saturation of retinal artery in diabetic group was significantly higher than that in normal group, and that in each quadrant of retinal artery in diabetic group was higher than that in normal group. There was significant difference between the infratemporal branch and the normal group (P 0.05). The retinal venous oxygen saturation in the diabetic group was higher than that in the normal group, but the difference was not statistically significant (P 0.05), the retinal vein blood oxygen saturation in the diabetic group was higher than that in the normal group, and the subnasal branch was lower than that in the normal group. The difference was statistically significant (P 0.05). The difference of retinal arteriovenous oxygen saturation in diabetic group was significantly higher than that in normal group. Conclusion there is significant difference between retina blood vessel oxygen saturation and healthy population in diabetic patients, and the changes of blood vessel oxygen saturation in different quadrants of diabetic patients are different. The results suggest that the degree of abnormal oxygen metabolism in the retina is not uniform in each quadrant.
【作者单位】：成都中医药大学眼科学院;
【基金】：国家重大科学仪器设备开发专项(编号:2013YQ490859)~~
【分类号】：R587.2;R774.1

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