糖尿病足溃疡患者截肢相关因素分析

发布时间：2018-04-30 23:09

本文选题：糖尿病足 + 溃疡　；参考：《重庆医学》2017年23期

【摘要】：目的探讨住院糖尿病足溃疡(DFU)患者截肢的相关因素,为降低DFU截肢风险提供理论依据。方法 2013年10月至2015年12月收治于该院的307例DFU患者,按是否接受截肢手术分为截肢组(28例)和非截肢组(279例),对两组患者的临床特征及实验室指标进行单因素分析,并采用多因素非条件Logistic回归分析探讨截肢的相关因素。结果截肢组患者的住院时间、超敏C反应蛋白(hs-CRP)及纤维蛋白原(FIB)水平均明显高于非截肢组(P0.05),血红蛋白(Hb)、高密度脂蛋白(HDL)及血清清蛋白(ALB)水平明显低于非截肢组(P0.05)。两组患者不同Wagner分级截肢情况分布比较差异也有统计学意义(P=0.000)。多因素非条件Logistic回归分析发现住院时间(OR=1.024;95%CI:1.009~1.039),Wagner分级(OR=2.779;95%CI:1.753~4.404)是DFU患者截肢的独立危险因素,HDL是DFU截肢的保护性因素(OR=0.161;95%CI:0.036~0.729)。结论 DFU患者Wanger分级越高,住院时间越长,截肢风险越高,HDL是DFU截肢的保护性因素。
[Abstract]:Objective to investigate the related factors of amputation of diabetic foot ulcer (DFU) patients in order to reduce the risk of DFU amputation. Methods from October 2013 to December 2015, 307 patients with DFU were divided into amputation group (n = 28) and non-amputation group (n = 279). Multivariate non-conditional Logistic regression analysis was used to study the related factors of amputation. Results in the amputation group, the levels of hypersensitive C-reactive protein hs-CRP (Hs-CRP) and fibrinogen (FIBs) were significantly higher than those in the non-amputation group (P 0.05), and the levels of HB, HDL and ALB in the amputation group were significantly lower than those in the non-amputation group (P 0.05). The distribution of amputation in different Wagner grades was also significantly different between the two groups (P < 0. 000). Multivariate conditional Logistic regression analysis showed that the length of stay in hospital was 1.009 (1.009) and 1.039 (Wagner grade) was an independent risk factor for amputation of DFU patients. It was the protective factor of DFU amputation. Conclusion the higher the Wanger grade, the longer the length of hospitalization and the higher the risk of amputation in DFU patients are the protective factors of DFU amputation.
【作者单位】：重庆医科大学附属第一医院内分泌内科;
【基金】：国家临床重点专科建设项目[财社(2011)170号] 重庆医科大学附属第一医院护理科研基金(HLJ2015-27)
【分类号】：R587.2

【相似文献】