糖尿病足患者治疗前后营养评分与溃疡愈合面积的关系

发布时间：2018-05-02 18:40

本文选题：糖尿病足 + 微型营养评价法　；参考：《广东医学》2017年13期

【摘要】：目的调查糖尿病足溃疡患者治疗前后的营养状况、C反应蛋白及溃疡转归等指标,并分析其相互关系及临床意义。方法应用微型营养评估法(MNA)对57例糖尿病足溃疡Wagner3级患者进行治疗前和治疗6周后营养评价,并同时检测患者的血红蛋白、血清白蛋白、C反应蛋白及溃疡愈合面积。结果 57例糖尿病足溃疡患者MNA得分为(16.36±3.68)分,其中发生营养不良43例(75.44%),潜在营养不良14例(24.56%);治愈13例、显效26例、有效18例,治愈、显效、有效患者治疗后营养状况评分、血红蛋白、血清白蛋白升高,溃疡面积、C反应蛋白降低,组内治疗前后营养状况评分、溃疡面积、C反应蛋白比较差异有统计学意义(P0.05);治愈患者与有效患者比较差异有统计学意义(P0.01)。营养评分与溃疡面积呈负相关(r=-0.28,P=0.03)、与C反应蛋白呈负相关(r=-0.26,P=0.03)。结论糖尿病足溃疡患者均存在营养状况不佳,并可能与其炎症状态密切相关,及时进行营养评估和改善营养状况,控制炎症状态,将有利于糖尿病足溃疡的愈合。
[Abstract]:Objective to investigate the nutritional status and prognosis of diabetic foot ulcer patients before and after treatment, and to analyze their relationship and clinical significance. Methods 57 cases of diabetic foot ulcers with Wagner3 grade were evaluated by micronutrition evaluation method. The hemoglobin, serum albumin C-reactive protein and ulcer healing area were also measured before and 6 weeks after treatment. Results the MNA score of 57 patients with diabetic foot ulcer was 16.36 卤3.68, among which 43 cases had malnutrition, 14 cases had latent malnutrition, 13 cases were cured, 26 cases were effective, 18 cases were effective. The levels of hemoglobin, serum albumin, ulcer area and C-reactive protein were increased, and the nutritional status before and after treatment were evaluated. There was significant difference in the area of ulcer (P 0.05) and the difference between cured patients (P 0.01) and effective patients (P 0.01). There was a negative correlation between nutritional score and ulcer area (r = 0.28) or C-reactive protein (n = 0.03), and a negative correlation between nutritional score and C-reactive protein (n = 0.03). Conclusion Diabetic foot ulcer patients have poor nutritional status and may be closely related to their inflammatory status. Timely nutritional evaluation and improvement of nutritional status and control of inflammatory status will be conducive to the healing of diabetic foot ulcer.
【作者单位】：佛山市中医院内分泌科;
【基金】：佛山市科技创新平台项目(编号:2015AG10014)
【分类号】：R587.2

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