2型糖尿病合并原发性高血压晨峰现象的影响因素

发布时间：2018-05-08 16:34

本文选题：型糖尿病 + 原发性高血压　；参考：《临床心血管病杂志》2017年04期

【摘要】：目的:研究合并有2型糖尿病的原发性高血压患者出现血压晨峰现象的相关影响因素。方法:随机选取武汉科技大学附属天佑医院2015-01-2016-06的111例符合条件的患者,根据24h动态血压(ABPM)结果,将患者分为血压晨峰组(MBPS组)38例,及非血压晨峰组(NMBPS组)73例;检测患者的血脂(TC、TG、LDL-C、HDL-C)、空腹血糖(FBG)、糖化血红蛋白(HbA1c)、颈动脉内膜-中层厚度(IMT)。对比分析两组患者以上相关数据。结果:两组患者在性别、吸烟、饮酒、年龄、高血压病程、糖尿病病程、TC、TG、LDL-C、HDL-C、FBG等方面的差异无统计学意义(P0.05);与NMBPS组相比较,MBPS组在BMI、HbA1c、IMT等方面数值升高,差异有统计学意义(P=0.011、0.042、0.001);Pearson相关分析显示BMI、IMT与MBPS呈正相关;多元线性回归分析显示BMI、IMT为血压晨峰现象的影响因素。结论:BMI及IMT是2型糖尿病合并原发性高血压患者血压晨峰现象的重要影响因素。
[Abstract]:Objective: to study the related factors of blood pressure morning peak in essential hypertension patients with type 2 diabetes mellitus. Methods: 111 eligible patients from Tianyou Hospital affiliated to Wuhan University of Science and Technology were randomly selected. According to the results of ABPM24 h ambulatory blood pressure (ABPM), the patients were divided into morning peak group (n = 38) and non-blood pressure group (n = 73). Serum lipids were measured in patients with TGG, FBGG, HbA1C, intima-media thickness of carotid artery (IMT), fasting blood glucose (FBGN), HbA1cn (HbA1cU), carotid artery intima-media thickness (IMT). The above data of two groups of patients were compared and analyzed. Results: there was no significant difference between the two groups in sex, smoking, drinking, age, duration of hypertension, and the course of diabetes. Pearson correlation analysis showed that there was a positive correlation between BMI-IMT and MBPS, and multiple linear regression analysis showed that BMI-IMT was the influencing factor of morning peak of blood pressure. Conclusion IMT and IMT are important influencing factors of blood pressure morning peak in patients with type 2 diabetes mellitus and essential hypertension.
【作者单位】：武汉科技大学附属天佑医院心内科;
【分类号】：R544.11;R587.1

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