呼吸功能训练对无创正压通气治疗重度急性有机氟中毒患者康复期肺功能影响

发布时间：2018-05-08 16:39

本文选题：呼吸功能训练 + 无创正压通气　；参考：《中国地方病防治杂志》2016年04期

【摘要】：目的分析研究对接受无创正压通气治疗的重度急性有机氟中毒患者实施呼吸功能训练对其肺功能的影响。方法62例重度急性有机氟中毒患者,随机分为观察组与对照组,各31例。两组患者均进行无创正压通气治疗,对照组仅进行日常锻炼,观察组进行缩唇-腹式呼吸及人工阻力呼吸训练,对比观察两组患者治疗效果、肺通气功能变化情况及治疗前后血清α-AT1、SP-D、NE、TGF-β1和生活质量变化情况。结果观察组治疗总有效率为93.55%,高于对照组的74.19%,且FEV1、FEV1与FVC比值、VC、DLco及MVV水平均明显优于对照组,差异有统计学意义(P0.05);治疗前两组血清中α-AT1、SP-D、NE、TGF-β1水平及生活质量评分比较,差异无统计学意义(P0.05);治疗后,观察组各项指标及生活质量评分均明显优于对照组,差异有统计学意义(P0.05)。结论重度急性有机氟中毒患者在无创正压通气治疗基础上采用呼吸功能训练,可有效改善血清各项指标,稀释体内毒性,恢复患者肺部功能,对提高其治疗效果和生活质量具有重要意义,值得推广运用。
[Abstract]:Objective to study the effects of respiratory function training on lung function in patients with severe acute organic fluorosis treated by non-invasive positive pressure ventilation. Methods Sixty-two patients with severe acute organic fluorosis were randomly divided into observation group and control group, 31 cases in each group. The patients in both groups were treated with non-invasive positive pressure ventilation, the control group was only given daily exercise, the observation group was trained with labial and ventral breathing and artificial resistance breathing, and the therapeutic effect was compared between the two groups. The changes of pulmonary ventilation function and the changes of serum 伪 -AT1, SP-DX, TGF- 尾 1 and quality of life before and after treatment. Results the total effective rate of treatment in the observation group was 93.55, which was higher than that in the control group (74.19%), and the ratio of FEV1FEV1 to FVC was significantly higher than that in the control group (P 0.05). After treatment, the indexes and quality of life scores in the observation group were significantly better than those in the control group, and the difference was statistically significant (P 0.05). Conclusion Respiratory function training on the basis of noninvasive positive pressure ventilation in patients with severe acute organic fluorosis can effectively improve the indexes of serum, dilute the toxicity in vivo and restore the pulmonary function of the patients. It is of great significance to improve the therapeutic effect and quality of life, and is worth popularizing.
【作者单位】：郑州铁路职业技术学院;
【分类号】：R595

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