FLARE问卷对类风湿关节炎的病情活动及识别复发中的临床研究

发布时间：2018-05-12 21:44

本文选题：Flare + 问卷　；参考：《中国地方病防治杂志》2017年04期

【摘要】：目的 FLARE问卷(FI)是综合患者及风湿专科医师观点,且能检测当前或近期类风湿关节炎RA复发的自我管理和识别工具,本研究通过对RA患者FI评分与病情活动性的相关性分析,探讨FI与RA病情活动度评分(DAS28)的相关性以及识别RA病情复发的情况。方法选择2014年8月-2015年9月在门诊随访或医院住院的RA患者166例作为研究对象,均符合美国风湿病学会(ACR)1987年RA诊断标准,使用DAS28作为金标准。回收158份完整FI调查问卷结果,将FI与RA病情活动度指标DAS28、CRP和ESR进行Spearman相关分析,绘制ROC曲线,计算曲线下面积。结果FI值和DAS28、ESR和CRP均有明显相关性,P0.05,FI的诊断特性以DAS28为金标准,ROC曲线下的面积是0.71,约登指数为0.70。结论研究结果表明FI与临床病情活动性指标DAS28、ESR、CRP的相关性较好,故FI有助于识别RA患者病情复发。
[Abstract]:Objective FLARE questionnaire is a comprehensive patient and rheumatologist's viewpoint, and can be used to detect the relapse of rheumatoid arthritis (RA) by self-management and identification tool. This study analyzed the correlation between fi score and disease activity in RA patients. To investigate the correlation between fi and RA activity score (DAS28) and to identify the recurrence of RA. Methods from August 2014 to September 2015, 166 RA patients who were followed up or hospitalized in outpatient department from August 2014 to September 2015 were selected as the study subjects. All of them were in accordance with the American Rheumatological Society (ACR) 1987 RA diagnostic criteria, and DAS28 was used as the gold standard. The results of 158 complete fi questionnaires were collected and Spearman correlation analysis was carried out between fi and RA disease activity index DAS28hCRP and ESR. The ROC curve was drawn and the area under the curve was calculated. Results there was a significant correlation between fi value and DAS28ESR and CRP. The diagnostic characteristics of FI were as follows: the area under the DAS28 curve was 0.71, and the Yorden index was 0.70. Conclusion the results of this study indicate that fi has a good correlation with the clinical activity index DAS28 ESR-CRP, so fi is helpful to identify the relapse of RA patients.
【作者单位】：西安市第五医院风湿免疫科;兰州大学第二医院风湿科;西安交通大学地方病研究所;
【基金】：西安市卫生科研项目(J2014014,J) 兰州市科技计划项目(项目编号:2015-2-56)
【分类号】：R593.22

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