糖尿病视网膜病变患者全视网膜激光光凝前后视网膜动、静脉循环时间的改变

发布时间：2018-05-14 01:36

  本文选题：糖尿病视网膜病变 + 全视网膜激光光凝　； 参考：《眼科新进展》2017年10期

【摘要】：目的观察糖尿病视网膜病变(diabetic retinopathy,DR)患者全视网膜激光光凝(pan-retinal laser photocoagulation,PRP)治疗前后视网膜动、静脉循环时间的改变。方法经荧光素眼底血管造影(fundus fluorescein angiography,FFA)检查确诊为重度非增殖期及增殖期DR且符合PRP适应证的16例(16眼)患者纳入研究,并行PRP。治疗前、治疗后1~3个月,采用FFA对所有患眼视网膜动、静脉循环时间进行记录,观察视网膜动脉4个分支主干出现显影的时间、完全充盈的时间,视网膜静脉4个分支主干全部出现层流的时间、完全充盈的时间,计算得出视网膜动脉、视网膜毛细血管、视网膜静脉、视网膜动静脉通过时间,对比观察治疗前后患眼不同时段的视网膜通过时间的变化。结果 DR患者PRP治疗前视网膜毛细血管通过时间为(1.58±0.99)s,治疗后为(2.19±1.23)s,差异有统计学意义(P=0.011)。DR患者PRP治疗前后的视网膜动脉、视网膜静脉、视网膜动静脉通过时间的差异均无统计学意义(均为P0.05)。结论 PRP是DR患者的最重要治疗方式,在PRP治疗后1~3个月视网膜毛细血管通过时间的血流动力学改变最为显著,较PRP治疗前有显著延长。
[Abstract]:Objective to observe the changes of circulation time of retinal artery and vein in diabetic retinopathy (Dr) patients before and after treatment with pan-retinal laser photocoagulation. Methods 16 patients (16 eyes) with severe nonproliferative phase and proliferative phase Dr diagnosed by fundus fluorescein angiography were included in the study. Before and 1 ~ 3 months after treatment, FFA was used to record the circulation time of retinal artery and vein in all the affected eyes. The time of development of the main branches of the retinal artery and the time of complete filling were observed. The time of laminar flow in all four branches of retinal vein and the time of complete filling were calculated, and the passage time of retinal artery, retinal capillary, retinal vein, retinal artery and vein was calculated. The changes of retinal transit time before and after treatment were observed. Results the retinal capillary transit time before and after PRP treatment in Dr patients was 1.58 卤0.99 s and 2.19 卤1.23 s, respectively. The difference was statistically significant in retinal artery and retinal vein before and after PRP treatment in Dr patients. There was no significant difference in retinal arteriovenous transit time (P 0.05). Conclusion PRP is the most important treatment method for Dr patients. The hemodynamic changes of retinal capillary transit time in 1 ~ 3 months after PRP treatment are the most significant, which is significantly longer than that before PRP treatment.
【作者单位】： 中国医科大学附属盛京医院眼科;
【分类号】：R587.2;R774.1
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本文编号：1885759