通痹方熏蒸疗法干预2型糖尿病下肢血管病变的临床研究

发布时间：2018-05-20 13:41

本文选题：通痹方 + 熏蒸疗法　；参考：《山东中医药大学》2015年硕士论文

【摘要】：目的:观察中药通痹方熏蒸疗法对2型糖尿病下肢血管病变的临床疗效,为临床辨证治疗提供方便可行的治疗依据。方法:将60例2型糖尿病下肢血管病变诊断的患者按1:1的比例随机分为治疗组和对照组。所有受试者接受治疗时均进行基础治疗(糖尿病知识普及、糖尿病饮食、运动疗法、降糖药物治疗),对照组进行基础治疗加普通温水熏蒸治疗,治疗组在基础治疗的同时加用中药通痹方熏蒸治疗。观察时间为6周。治疗前后监测患者的临床症状积分、血糖、血脂以及踝肱比值(ABI指数),检测肝肾功能及血常规。结果:1.治疗组中医症状改善较治疗前有明显改善(P0.05),治疗后两组间比较有差异性(P0.05)。治疗组综合疗效总有效率为90.00%,对照组为53.33%,两组间比较有差异性(P0.05)。2.两组在降低血糖、糖化血红蛋白方面均有较好的疗效,治疗前后比较有显著差异(P0.05),但组间比较无差异性(P0.05)。3.通痹方熏蒸法在降低胆固醇、甘油三酯,改善踝肱比(ABI)方面都有较好的疗效,组间比较有差异性(P0.05)。4.治疗前后两组肝肾功能及血常规无差异,组间比较无差异(P0.05)。结论:运用通痹方熏蒸疗法治疗2型糖尿病下肢血管病变缓解了临床症状,改善ABI指数,临床效果显著。治疗过程中用药安全,无不良反应发生,值得临床推广。
[Abstract]:Objective: to observe the clinical effect of Tongbi prescription fumigation on vascular disease of lower extremity of type 2 diabetes mellitus, and to provide convenient and feasible treatment basis for clinical treatment based on syndrome differentiation. Methods: 60 patients with type 2 diabetes mellitus were randomly divided into treatment group and control group. All subjects were treated with basic treatment (diabetes knowledge popularization, diabetes diet, exercise therapy, hypoglycemic drug therapy, control group, basic treatment plus general warm water fumigation, The treatment group was treated by fumigation with Tongbi prescription in addition to basic treatment. The observation time was 6 weeks. The clinical symptom score, blood glucose, blood lipid and ankle-brachial ratio were monitored before and after treatment, and the liver and kidney function and blood routine were detected. The result is 1: 1. The improvement of TCM symptoms in the treatment group was significantly better than that before treatment (P 0.05), and the difference between the two groups after treatment was significant (P 0.05). The total effective rate was 90.00g in the treatment group and 53.33g in the control group. There was a difference between the two groups. The two groups had better curative effect in reducing blood sugar and glycosylated hemoglobin. There was significant difference between the two groups before and after treatment, but there was no difference between the two groups. Tongbi recipe fumigation method in reducing cholesterol, triglyceride, improve the ankle-brachial ratio of ABI) has a better effect, there is a difference between the groups, P0.05. 4. There was no difference in liver and kidney function and blood routine between the two groups before and after treatment, but there was no difference between the two groups (P 0.05). Conclusion: Tongbi prescription fumigation therapy can relieve the clinical symptoms and improve the ABI index in patients with type 2 diabetes mellitus. In the course of treatment, drug use is safe and no adverse reactions occur, so it is worth popularizing in clinic.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R587.2

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