老年2型糖尿病患者并发肺部感染的病原菌分布及危险因素分析
发布时间:2018-05-21 02:39
本文选题:老年 + 型糖尿病 ; 参考:《现代预防医学》2017年13期
【摘要】:目的探讨老年2型糖尿病患者并发肺部感染的病原菌分布特征及其相关危险因素。方法选取该院老年2型糖尿病并发肺部感染患者426例作为病例组和同期老年2型糖尿病未并发肺部感染患者430例作为对照组,采用法国生物梅里埃VITEK-60全自动细菌分析仪分离和鉴定菌株,应用多因素Logistic回归分析老年2型糖尿病患者并发肺部感染的危险因素。结果 426例肺部感染患者共分离出病原菌471株,以革兰阴性菌(63.27%)和革兰阳性菌(27.18%)为主。多因素logistic回归分析显示,年龄、侵袭性操作、FBG水平高、Alb水平低、APACHEⅡ评分高是肺部感染患者的独立危险因素(P0.05)。ROC曲线评价Logistic回归模型预测效果的曲线下面积(AUC)及95%CI为0.912(0.853~0.986)。结论老年2型糖尿病患者并发肺部感染的病原菌分布较广,影响肺部感染的危险因素较多,需早期预防及控制,以降低患者发生感染的机率。
[Abstract]:Objective to investigate the distribution and risk factors of pathogenic bacteria in elderly type 2 diabetes mellitus complicated with pulmonary infection. Methods 426 elderly patients with type 2 diabetes mellitus complicated with pulmonary infection were selected as case group and 430 elderly patients with type 2 diabetes without pulmonary infection as control group. The strains were isolated and identified by VITEK-60 automatic bacterial analyzer. Multivariate Logistic regression analysis was used to analyze the risk factors of pulmonary infection in elderly patients with type 2 diabetes. Results A total of 471 strains of pathogenic bacteria were isolated from 426 patients with pulmonary infection, mainly Gram-negative bacteria (63.27) and Gram-positive bacteria (27.18). Multivariate logistic regression analysis showed that age, high invasive operation, high Alb and low Apache 鈪,
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