亚临床甲状腺功能减退患者血清抵抗素及血脂水平变化及意义

发布时间：2018-05-30 12:15

本文选题：亚临床甲状腺功能减退症 + 抵抗素　；参考：《山东医药》2016年14期

【摘要】：目的探讨亚临床甲状腺功能减退症(简称亚临床甲减)患者血清抵抗素、血脂水平的变化及意义。方法选择亚临床甲减患者50例作为亚临床甲减组,选择同期体检的健康体检者48例作为对照组。采集两组空腹静脉血,采用ELISA法检测血清抵抗素水平,全自动生化分析仪检测血脂(包括TG、TC、HDL、LDL)水平。结果对照组血清抵抗素、TG、TC、HDL、LDL水平分别为(9.65±2.37)μg/L、(1.13±0.48)mmol/L、(4.57±0.68)mmol/L、(1.30±0.31)mmol/L、(2.87±0.43)mmol/L,亚临床甲减组分别为(8.31±3.02)μg/L、(2.04±1.75)mmol/L、(5.91±2.33)mmol/L、(1.18±0.20)mmol/L、(2.94±0.41)mmol/L,亚临床甲减组血清抵抗素水平低于对照组,血清TG、TC、LDL水平均高于对照组(P均0.05),两组血清HDL差异无统计学意义。结论亚临床甲减患者已出现血脂代谢异常,可能与血清抵抗素水平降低有关。
[Abstract]:Objective to investigate the changes and significance of serum resistin and blood lipid in subclinical hypothyroidism (subclinical hypothyroidism). Methods 50 subclinical hypothyroidism patients were selected as subclinical hypothyroidism group and 48 cases of healthy physical examination in the same period were selected as control group. Two groups of fasting venous blood were collected, and ELISA method was used to detect the blood serum. The levels of serum lipids (including TG, TC, HDL, LDL) were detected by automatic biochemical analyzer. Results the level of serum resistin, TG, TC, HDL and LDL in the control group was (9.65 + 2.37) micron, (1.13 + 0.48) mmol/L, (4.57 + 0.68) mmol/L, (1.30 + 0.31) mmol/L, (2.87 + 0.43) and (8.31 + 3.02), respectively. 2.33) mmol/L, (1.18 + 0.20) mmol/L, (2.94 + 0.41) mmol/L, the level of serum resistin in subclinical hypothyroidism group was lower than that of the control group. The level of serum TG, TC and LDL was higher than that of the control group (P 0.05). The difference of serum HDL in the two groups was not statistically significant.
【作者单位】：河北医科大学第一医院;
【基金】：河北省科技支撑计划资助项目(11276139)
【分类号】：R581.2

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