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2型糖尿病患者腹胀与小肠细菌过度生长的关系

发布时间:2018-05-31 13:45

  本文选题:型糖尿病 + 小肠细菌过度生长 ; 参考:《山东大学学报(医学版)》2016年01期


【摘要】:目的探讨2型糖尿病患者腹胀与小肠细菌过度生长(SIBO)的关系。方法将96例2型糖尿病患者分为血糖正常且无腹胀组、血糖正常并腹胀组、血糖升高无腹胀组、血糖升高并腹胀4组,通过乳果糖氢呼气试验分别检测其SIBO情况及口盲时间,并与健康对照组进行组间比较分析。结果血糖升高并腹胀组患者的SIBO阳性率较其他组患者明显增高,差异有统计学意义。腹胀组SIBO阳性率与健康对照组比较有统计学差异(P0.05),4组患者口盲时间与健康对照组比较均有统计学意义(P0.01)。结论 2型糖尿病合并腹胀患者易发生SIBO,与口盲时间延长相关,其可能是腹胀发生的重要发病机制。
[Abstract]:Objective to investigate the relationship between abdominal distension and intestinal bacterial overgrowth in type 2 diabetes mellitus. Methods 96 patients with type 2 diabetes mellitus were divided into 4 groups: normal blood glucose and no abdominal distension group, normal blood glucose with abdominal distention group, no abdominal distention group with elevated blood glucose, and 4 groups with elevated blood glucose and abdominal distention. The SIBO and oral blindness time were measured by hydrogen breath test of lactulose. And compared with the healthy control group. Results the positive rate of SIBO in patients with hyperglycemia and abdominal distension was significantly higher than that in other groups. The positive rate of SIBO in the abdominal distension group was significantly higher than that in the healthy control group (P 0.05) and the time of oral blindness in the 4 groups was significantly higher than that in the healthy control group (P 0.01). Conclusion SIBO is easy to occur in type 2 diabetes mellitus patients with abdominal distension, which may be an important pathogenesis of abdominal distension.
【作者单位】: 东莞东华医院消化内科;河南大学护理学院;
【分类号】:R587.1


本文编号:1959948

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