甘肃省成年人维生素D状况调查

发布时间：2018-06-10 02:41

  本文选题：25羟维生素D/25(0H)D + 维生素D缺乏　； 参考：《宁夏医科大学》2017年硕士论文

【摘要】：目的:调查目前甘肃省健康成人的维生素D水平状况,并分析维生素D缺乏的危险因素,评价其与代谢性相关因素的关系,为防治维生素D缺乏提供流行病学依据。方法:采用整群分层随机的抽样调查方法,于2014年6月至2015年11月,在甘肃省7个地区抽取18-79岁5年以上的常住居民11 300人,并对其进行问卷调查、物理测量、生化检查和骨密度检测。并对数据资料进行统计学分析。结果:1.共有11 157名(男性4 740名,女性6 417名)调查对象完成该项研究。2.总人群的血清25(0H)D平均水平为13.8(11.0,17.8)ng/m L。3.维生素D严重缺乏(10ng/m L)、缺乏(10-20ng/m L)、不足(20-30ng/m L)、正常(≥30 ng/m L)现患率分别为17.3%,64.6%,11.8%和6.3%。4.维生素D缺乏的独立危险因素包括年龄、性别,而日照、运动和钙剂的补充为保护性因素(P0.05)。5.血清25(OH)D的水平与血清甲状旁腺激素呈负相关(r=-0.279,P0.001),与血钙(r=0.239,P0.01),血磷(r=0.090,P=0.018),血清低密度脂蛋白(r=0.100,P=0.008)和BMI(r=0.093,P=0.014)呈正相关。在所有受试者中,血清25(OH)D的水平与BMD无统计学差异(P0.05)。结论:维生素D缺乏普遍存在于甘肃地区成年人群,尤其多见于女性和较年轻者,并受日照、活动、钙剂等因素影响,需要采取积极的综合措施进行干预。
[Abstract]:Objective: to investigate the status of vitamin D levels in healthy adults in Gansu Province at present, analyze the risk factors of vitamin D deficiency, evaluate the relationship between vitamin D deficiency and metabolic factors, and provide epidemiological basis for the prevention and treatment of vitamin D deficiency. Methods: from June 2014 to November 2015, 11 300 permanent residents aged 18 to 79 years were selected from 7 districts of Gansu Province by cluster stratified random sampling, and were investigated by questionnaire and physical measurement. Biochemical examination and bone mineral density test. The data were analyzed statistically. The result is 1: 1. A total of 11,157 subjects (4,740 males and 6,417 females) completed the study. The average serum concentration of 25g / mg / ml 路L ~ (-1) D in the total population was 13.8ng / mL ~ (-1) and 17.8ng / mL ~ (-1) 路m ~ (-1). Vitamin D was severely deficient in 10 ng / m L ~ (-1), 10 ~ (-20) ng / m ~ (-1) L ~ (-1), 20 ~ (30) ng / m ~ (-1) L ~ (-1). The prevalence rates of normal (鈮，

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