江苏某高校教工高尿酸血症及相关性分析

发布时间：2018-06-18 18:46

本文选题：高尿酸血症 + 体检　；参考：《东南大学学报(医学版)》2017年05期

【摘要】：目的:探讨江苏某高校教工高尿酸血症(HUA)患病率及相关危险因素。方法:以参加某高校2016年5月至11月体检的教工为研究对象,进行各项体检及生化指标测定。结果:该群体HUA患病率为20.8%,男性显著高于女性(P0.01)。HUA患者的年龄、体质量指数、腰围等8项指标均高于尿酸正常者,而估算的肾小球滤过率低于尿酸正常者(P0.05)。多因素Logistic回归模型显示男性、肥胖、腹型肥胖、高血压、肾功能严重受损、低高密度脂蛋白血症与血尿酸水平呈正相关(P0.05)。HUA患者合并3项及以上心血管病危险因素的比例高于尿酸正常者(P0.05)。结论:男性、肥胖、腹型肥胖、高血压、肾功能严重受损、低高密度脂蛋白血症是HUA独立危险因素,而HUA合并心血管病危险因素有聚集性,应采取综合措施尽早干预HUA发生发展。
[Abstract]:Objective: to investigate the prevalence of hyperuricemia and its related risk factors. Methods: the teachers who took part in the physical examination of a university from May to November 2016 were selected as the research objects, and the physical examination and biochemical indexes were measured. Results: the prevalence rate of Bua in this population was 20.80.The age, body mass index and waist circumference of male patients were significantly higher than those of female patients with P0.01HUA, and the estimated glomerular filtration rate was lower than that of patients with normal uric acid (P0.05). Multivariate logistic regression model showed that male, obese, abdominal obesity, hypertension, renal function damage, There was a positive correlation between low density lipoproteinemia and serum uric acid level. The proportion of three or more risk factors of cardiovascular disease in patients with low density lipoproteinemia and serum uric acid level was higher than that in patients with normal uric acid. Conclusion: male, obesity, abdominal obesity, hypertension, severe impairment of renal function, low density lipoproteinemia are independent risk factors of Hua. Comprehensive measures should be taken to interfere with the occurrence and development of HUA as soon as possible.
【作者单位】：东南大学医院;东南大学公共卫生学院;
【分类号】：R589.7

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