慢性丙型肝炎病毒感染者2型糖尿病患病情况及相关因素分析

发布时间：2018-06-19 14:17

本文选题：慢性丙型肝炎病毒 + 病毒性肝炎　；参考：《山东医药》2017年26期

【摘要】：目的调查慢性丙型肝炎病毒(HCV)感染者2型糖尿病(T2DM)患病情况,并分析相关危险因素。方法随机选取187例成年慢性HCV感染者,进行问卷调查、体格检查(身高、体质量,计算BMI)、生活方式(是否饮酒、吸烟等)及血生化指标(血糖、血脂、肝功能及HCV-RNA)检测,并对相关因素进行单因素、多因素Logistic回归分析。结果 187例慢性HCV感染者中确诊为T2DM者24例,T2DM患病率为12.83%。单因素分析发现,慢性HCV感染者的年龄、文化程度、BMI、油脂和果蔬摄入量、TC、TG、LDL-C、GGT、HCV-RNA与T2DM的患病有关(P均0.05);多因素分析发现,年龄(OR=1.792)、BMI(OR=1.515)、果蔬摄入量(OR=1.375)、TG(OR=1.571)、TC(OR=1.421)、LDL-C(OR=1.225)与慢性HCV感染者T2DM患病独立相关(P均0.05)。结论慢性HCV感染者T2DM患病率较高,尤其年龄较大、肥胖、蔬果摄入不足及合并脂肪肝者。
[Abstract]:Objective to investigate the prevalence of type 2 diabetes mellitus (T2DM) in patients with chronic hepatitis C virus (HCV) infection and to analyze the related risk factors. Methods 187 adult patients with chronic HCV infection were randomly selected for questionnaire survey, physical examination (height, body mass, BMIA), lifestyle (drinking, smoking, etc.) and blood biochemical indexes (blood glucose, blood lipid, liver function and HCV-RNAs). Univariate and multivariate logistic regression analysis was used to analyze the related factors. Results the prevalence of T2DM was 12.83 in 24 of 187 patients with chronic HCV infection. Univariate analysis showed that the age and educational level of patients with chronic HCV infection were significantly higher than that of BMIs, the levels of oil and vegetable intake (TCN) TGG LDL-CGTV HCV-RNA were all related to the prevalence of T2DM (P < 0.05), and the multivariate analysis showed that the age of patients infected with HCV was 1.792Mi OR1.51515, and the intake of fruits and vegetables (OR1.375TGN) was 1.571g / l), and the independent correlation between T2DM and T2DM was 0.05% (P = 0.05). Conclusion the prevalence of T2DM in patients with chronic HCV infection is higher, especially in patients with older age, obesity, insufficient intake of fruits and vegetables and fatty liver.
【作者单位】：青海省第四人民医院;
【分类号】：R512.63;R587.1

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