100μT极低频电磁场对SD大鼠血液生化和肝肾功能的影响

发布时间：2018-08-05 20:31

【摘要】：为了明确长时间的极低频电磁场(ELF-EMFs)暴露对SD大鼠血液生化和肝肾功能的影响,制作了1个可以稳定产生均匀磁场(磁感应强度为100μT)的装置,并将128只SD大鼠暴露于其中,每天暴露20 h时间,共暴露12周时间,同时采用128只未接受暴露的SD大鼠作为对照。暴露期间每隔4周时间进行了SD大鼠血液生化检测。暴露结束后,取SD大鼠的肝脏、肾脏进行了组织形态学染色和检测。血液生化检测结果显示:电磁场暴露对SD大鼠肝功能(谷丙转氨酶和谷草转氨酶)、肾功能(血尿素氮和肌酐)、血糖、血脂(总胆固醇、总甘油三酯、高密度脂蛋白和低密度脂蛋白)、血电解质(钙离子和镁离子)均没有影响。组织形态学检测结果显示:肝脏的苏木素-伊红染色提示极低频电磁场暴露对SD大鼠的肝脏正常结构没有影响,炎性细胞染色结果提示暴露组SD大鼠肝脏中无明显炎性细胞浸润;类似地,肾脏的苏木素-伊红染色结果提示极低频电磁场暴露对SD大鼠的肾脏结构没有影响,马松染色结果提示暴露组SD大鼠肾脏中无明显纤维化病变。由此可得结论:极低频电磁场暴露对SD大鼠血液生化和肝肾功能没有影响。
[Abstract]:In order to determine the effect of prolonged exposure to extremely low frequency electromagnetic field (ELF-EMFs) on blood biochemistry and liver and kidney function of SD rats, a device was made to produce a stable uniform magnetic field (100 渭 T), and 128 SD rats were exposed to it. The rats were exposed for 20 hours a day for 12 weeks, and 128 SD rats without exposure were used as control. The blood biochemistry of SD rats was measured every 4 weeks during exposure. After exposure, the liver and kidney of SD rats were stained with histomorphology. The results of blood biochemistry test showed that electromagnetic field exposure to SD rats liver function (alanine aminotransferase and alanine aminotransferase), renal function (blood urea nitrogen and creatinine), blood glucose, blood lipids (total cholesterol, total triglyceride), High density lipoprotein (HDL) and low density lipoprotein (LDL), blood electrolytes (calcium ion and magnesium ion) have no effect. The results of histomorphology showed that the hematoxylin-eosin staining of the liver showed that the very low frequency electromagnetic field exposure had no effect on the normal structure of the liver in SD rats. The results of inflammatory cell staining showed that there was no obvious inflammatory cell infiltration in the liver of SD rats in the exposed group, and similarly, the hematoxylin-eosin staining in the kidney showed that very low frequency electromagnetic field exposure had no effect on the renal structure of SD rats. The results of Ma Song staining showed that there was no obvious fibrosis in the kidney of SD rats in exposed group. It is concluded that very low frequency electromagnetic field exposure has no effect on blood biochemistry and liver and kidney function of SD rats.
【作者单位】：电网环境保护国家重点实验室;中国电力科学研究院;华中科技大学同济医学院附属同济医院心血管内科;

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