碘超足量地区吸烟与甲状腺关系的研究

发布时间：2018-08-17 19:10

【摘要】：目的探讨碘超足量地区中、老年人群不同吸烟状态与甲状腺的关系及其他相关影响因素。方法于2011年随机抽取贵阳市40~80岁常驻居民共10 140例,进行问卷调查、体格、生化及甲状腺B超检查。应用回归分析比较不同吸烟状态与甲状腺体积、促甲状腺素(TSH)、甲状腺肿和甲状腺结节之间的关系及其他相关因素。结果经排除,共纳入研究对象6 122例;经分析,曾经吸烟、目前吸烟及男性与TSH呈负相关(P0.05);目前吸烟、男性、体质量指数与甲状腺体积呈正相关(P0.05);吸烟与甲状腺肿、甲状腺结节的患病率均无关(P0.05),年龄、女性是甲状腺结节的危险因素(P0.05)。结论吸烟可影响促甲状腺素水平,目前吸烟者有着较大的甲状腺体积,吸烟与甲状腺肿、甲状腺结节的患病率均无关。
[Abstract]:Objective to investigate the relationship between different smoking status and thyroid gland and other related factors in iodine excess population. Methods A total of 10 140 resident residents aged 4080 in Guiyang City were randomly selected in 2011 and investigated with questionnaire, physique, biochemistry and thyroid B ultrasonic examination. Regression analysis was used to compare the relationship between smoking status and thyroid volume, thyrotropin (TSH), goiter and thyroid nodules and other related factors. Results A total of 6,122 subjects were included in the study. After analysis, there was a negative correlation between smoking and TSH (P0.05), a positive correlation between body mass index (BMI) and thyroid volume (P0.05), smoking and goiter (P0.05). The prevalence of thyroid nodule was not significant (P0.05), age and female were the risk factors of thyroid nodule (P0.05). Conclusion smoking can affect the level of thyrotropin. At present, smokers have a large thyroid volume, smoking has no relationship with goiter and thyroid nodule prevalence.
【作者单位】：贵州医科大学附属医院内分泌代谢病科;
【基金】：贵州省科技合作计划项目(黔科合LH[2015]7413号) 贵州省省长资金临床应用课题专项研究(黔省专合字2012-100号)
【分类号】：R581.9

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