可减轻体重的降糖药物研究进展
发布时间：2018-08-25 17:27
【摘要】：正肥胖与糖尿病(DM)关系密切,是2型DM(T2DM)的危险因素之一。多数T2DM患者体型肥胖或超重,流行病学研究表明,在T2DM自然病程早期,肥胖者常表现有胰岛素抵抗(IR)和糖调节受损。减轻体重有助于控制血糖、降低DM并发症发生率和死亡率~([1])。肥胖的T2DM患者在选择降糖药物时,不仅要能有效地降糖,且应不增加体重甚至降低体重~([2])。本文综述能帮助患者维持合理体质量的降糖药物。
[Abstract]:Positive obesity is closely associated with diabetes mellitus (DM) and is one of the risk factors of type 2 DM (T2DM). Most T2DM patients are obese or overweight. Epidemiological studies show that the obese patients often exhibit insulin resistance, (IR) and impaired glucose regulation in the early stage of T2DM. Weight loss helps to control blood sugar, reduce the incidence of DM complications and mortality. Obese T2DM patients should not only be able to reduce glucose effectively, but also not gain weight or even lose weight when choosing hypoglycemic drugs. This article reviews hypoglycemic drugs that can help patients maintain reasonable body mass.
【作者单位】： 淄博市中心医院药学部;
【分类号】：R587.1;R589.2
本文编号：2203589
[Abstract]:Positive obesity is closely associated with diabetes mellitus (DM) and is one of the risk factors of type 2 DM (T2DM). Most T2DM patients are obese or overweight. Epidemiological studies show that the obese patients often exhibit insulin resistance, (IR) and impaired glucose regulation in the early stage of T2DM. Weight loss helps to control blood sugar, reduce the incidence of DM complications and mortality. Obese T2DM patients should not only be able to reduce glucose effectively, but also not gain weight or even lose weight when choosing hypoglycemic drugs. This article reviews hypoglycemic drugs that can help patients maintain reasonable body mass.
【作者单位】： 淄博市中心医院药学部;
【分类号】：R587.1;R589.2
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