肥胖对成年人心脏功能及运动变化特征的影响

发布时间：2018-09-01 10:19

【摘要】：目的:评价肥胖成人安静及运动状态下心脏结构和功能的特点,旨在评估心脏改变的风险性和不良后果。方法:选取130名40~60岁的北京市居民(男n=29,女n=101),依照BMI分类标准,分成体重正常组(n=57)、超重组(n=56)、肥胖组(n=17)。每名受试者蹬骑卧式功率车进行起始25 W,每2 min递增25 W的运动,每等级运动结束前30 s及恢复期测定超声心动图。结果:1)与体重正常组相比,肥胖组舒张末期室间隔厚度(IVSd)、左心室舒张末期内径(LVIDd)、舒张末期左室后壁厚度(LVPWd)、左心室舒张末期容积(EDV)、左心室质量(LVM)、左心室质量指数(LVMI)、心率(HR)、每搏量(SV)、心输出量(CO)均非常显著性增加(P0.01)。2)肥胖成人发生左心室肥厚的比例远高于体重正常者和超重者。3)运动过程中肥胖者CO、SV非常显著性高于体重正常组(P0.01),EF、HR无显著性差异(P0.05)。结论:超重可引起心脏肥大,左室收缩功能异常,并随超重向肥胖过渡而加重。肥胖者运动中每搏量、心输出量较高,但心功能储备低于体重正常者,且运动后心率恢复受损。肥胖者安静及运动状态下心脏功能异常增强的原因尚需进一步深入研究。
[Abstract]:Objective: to evaluate the characteristics of cardiac structure and function in obese adults under quiet and exercise conditions, and to evaluate the risk and adverse consequences of cardiac changes. Methods: 130 Beijing residents aged 40 to 60 years (male nong 29, female nong 101) were divided into normal weight group (n = 57), superrecombinant group (n = 56) and obese group (n = 17) according to BMI classification criteria. Each participant was used for 25 wattage, 25 W for every 2 min, 30 seconds before the end of each grade of exercise, and 30 seconds before the end of each grade of exercise, and the echocardiography was measured during the convalescence period. Results: 1) compared with the normal weight group, Obesity group end diastolic septal thickness (IVSd), left ventricular end diastolic diameter (LVIDd), end diastolic left ventricular posterior wall thickness (LVPWd), left ventricular end diastolic volume (EDV), left ventricular mass (LVM), left ventricular mass index (LVMI), heart rate (HR), (SV), cardiac output (CO) The incidence of left ventricular hypertrophy in obese adults was significantly higher than that in normal and overweight subjects (P0.01). The CO,SV of obese subjects during exercise was significantly higher than that of normal subjects (P0.01). There was no significant difference between obese adults and obese adults during exercise (P0.05). Conclusion: overweight may lead to cardiac hypertrophy, abnormal left ventricular systolic function and increase with the transition from overweight to obesity. The cardiac output per stroke volume was higher in obese subjects, but the cardiac function reserve was lower than that of normal body weight, and the heart rate was impaired after exercise. The causes of abnormal enhancement of cardiac function in obese patients during quiet and exercise need further study.
【作者单位】：北京体育大学运动与体质健康教育部重点实验室;
【基金】：“十二五”国家科技支撑计划课题资助项目(2012BAK21B01)
【分类号】：R589.2

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