强直性脊柱炎与牙周炎相关性研究

发布时间：2018-09-02 06:15

【摘要】：目的探讨强直性脊柱炎(AS)与牙周炎(CP)的关系。方法收集2014年12月至2016年5月中国医科大学附属盛京医院收治的强直性脊柱炎患者100例,其中强直性脊柱炎合并牙周炎66例,单纯强直性脊柱炎34例。同时收集单纯牙周炎组患者45例,比较三组牙周参数、临床资料及临床指标。结果强直性脊柱炎合并牙周炎组C-反应蛋白、红细胞沉降率、BASDAI评分高于强直性脊柱炎无牙周炎组,且红细胞沉降率(ESR)差异有统计学意义。强直性脊柱炎人类白细胞抗原(HLA)-B27阳性组与强直性脊柱炎HLA-B27阴性组牙周参数比较差异无统计学意义。牙周炎合并强直性脊柱炎组与单纯牙周炎组的牙周参数探测深度(PD)、附着丧失(CAL)、ESR比较差异有统计学意义。结论牙周炎对强直性脊柱炎的病情可能有一定影响;强直性脊柱炎对于牙周炎也可能存在一定的影响。
[Abstract]:Objective to investigate the relationship between (AS) and (CP) in patients with ankylosing spondylitis. Methods from December 2014 to May 2016, 100 cases of ankylosing spondylitis were collected, including 66 cases of ankylosing spondylitis with periodontitis and 34 cases of simple ankylosing spondylitis. The periodontal parameters, clinical data and clinical indexes were compared among 45 patients with simple periodontitis. Results the C-reactive protein and erythrocyte sedimentation rate in ankylosing spondylitis with periodontitis group were higher than those without periodontitis group, and there was significant difference in erythrocyte sedimentation rate (ESR). There was no significant difference in periodontal parameters between (HLA) -B27 positive group and HLA-B27 negative group in ankylosing spondylitis. There was significant difference between periodontitis combined with ankylosing spondylitis group and simple periodontitis group in periodontal parameter detection depth (PD), attachment loss (CAL). Conclusion periodontitis may have some effect on the condition of ankylosing spondylitis and ankylosing spondylitis may have some effect on periodontitis.
【作者单位】：中国医科大学附属盛京医院风湿免疫科;
【基金】：辽宁省科学计划项目(编号2015020546)
【分类号】：R593.23;R781.42

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