低频脉冲电磁场治疗绝经后骨质疏松症的临床疗效观察

发布时间：2018-09-16 21:40

【摘要】：目的:采用低频脉冲电磁场(pulsed electromagnetic fields,PEMFs)对绝经后骨质疏松症患者进行干预,观察其临床疗效并进行为期1年的疗效观察,以探讨PEMFs对骨质疏松患者的短期和远期疗效。方法:将纳入研究的绝经后骨质疏松患者60例分为对照组和研究组。对照组接受为期12个月的常规骨质疏松治疗,包括钙剂、维生素D和二膦酸盐;研究组接受常规治疗的基础上增加30次(1个月)的PEMFs治疗。所有患者在治疗前和治疗后第1、3、6和12个月接受疗效评估,包括疼痛、功能受限指数。腰椎骨密度检查在治疗前,治疗后3、6和12个月接受检查。结果:纳入患者基线水平无显著性差异(P0.05)。治疗后1、3、6和12个月,研究组患者疼痛和功能受限的水平显著低于对照组;治疗后3个月研究组患者骨密度(bone mass density,BMD)改善明显高于对照组,而治疗后6和12个月两组的BMD没有显著性差异。结论:在常规药物治疗的基础上配合PEMFs治疗可在短期内增加对骨质疏松症患者疼痛和运动功能的改善作用且具有较好的远期疗效;对于腰椎骨密度的影响具有较好的效果,但是远期效果不明显。
[Abstract]:Objective: to investigate the short and long term effects of low frequency pulsed electromagnetic field (pulsed electromagnetic fields,PEMFs) on postmenopausal osteoporosis patients by observing its clinical effect and 1 year's curative effect. Methods: 60 postmenopausal osteoporosis patients were divided into control group and study group. The control group received 12 months of routine osteoporosis treatment, including calcium, vitamin D, and diphosphonates, while the study group received 30 additional times (1 month) of PEMFs on the basis of routine treatment. All patients were evaluated before and after treatment for 6 and 12 months, including pain and dysfunction index. Lumbar bone mineral density was examined 3 months and 12 months before treatment. Results: there was no significant difference in baseline level (P0.05). The levels of pain and limited function in the study group were significantly lower than those in the control group 1 and 12 months after treatment, and the improvement of bone mineral density (bone mass density,BMD) in the study group was significantly higher than that in the control group 3 months after treatment. There was no significant difference in BMD between the two groups 6 and 12 months after treatment. Conclusion: on the basis of routine drug therapy combined with PEMFs treatment can improve the pain and motor function of patients with osteoporosis in the short term and has a good long-term effect on the effect of lumbar bone mineral density. But the long-term effect is not obvious.
【作者单位】：四川大学华西医院康复医学科康复医学四川省重点实验室;
【分类号】：R685;;R493

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