超声在2.0～4.0mm甲状腺良、恶性微小结节鉴别诊断中的价值

发布时间：2018-10-14 10:01

【摘要】：目的 :探讨超声在2.0~4.0 mm甲状腺良、恶性微小结节鉴别诊断中的价值。方法 :回顾分析经手术及病理证实的359例共412枚最大径在2.0~4.0 mm甲状腺微小结节的超声资料,其中甲状腺微小乳头状癌(PTMC)173例共194枚,微小结节性甲状腺肿(MNG)179例共204枚,PTMC合并MNG 7例共PTMC 7枚和MNG 7枚,观察结节形态不规则、低回声、纵横比≥1和微钙化在PTMC和MNG中的分布。结果:结节形态不规则(χ~2=261.967,P0.05)、低回声(χ~2=17.259,P0.05)、纵横比≥1(χ~2=249.703,P0.05)在2.0~4.0 mm PTMC与MNG中均具有统计学差异,微钙化无统计学差异(χ~2=1.155,P0.05)。纵横比≥1的特异度(92.9%)、阳性预测值(91.9%)、准确度(88.8%)均最高,形态不规则阴性预测值最高(94.4%),低回声的敏感度(97.0%)最高,其特异度(14.7%)最低。结论:在2.0~4.0 mm PTMC和MNG的鉴别诊断中,形态不规则和纵横比≥1是两个重要征象,尽管低回声对PTMC具有高度的敏感度,但特异度低而限制其临床应用。
[Abstract]:Objective: to evaluate the value of ultrasonography in differential diagnosis of benign and malignant thyroid nodules at 2.0 ~ 4.0 mm. Methods: the ultrasonographic data of 412 thyroid nodules with the maximum diameter of 2.0 ~ 4.0 mm confirmed by surgery and pathology were retrospectively analyzed, including 194 (PTMC) in 173 cases of thyroid micropapillary carcinoma. There were 204 (MNG) in 179 cases of minimal nodular goiter, 7 PTMC and 7 MNG in 7 cases of PTMC combined with MNG. The distribution of irregular shape, low echo, aspect ratio 鈮，

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