2型糖尿病微血管病变患者甲襞微循环积分变化及意义

发布时间：2018-10-25 15:38

【摘要】：目的探讨2型糖尿病微血管病变患者甲襞微循环积分的变化及意义。方法选择2型糖尿病患者353例,根据是否存在糖尿病视网膜病变(DR)分为眼底正常组(NDR组)、非增殖性DR组(NPDR组)、增殖性DR组(PDR组),根据是否存在糖尿病肾病(DN)分为正常白蛋白尿组(NDN组)、微量白蛋白尿组(EDN组)、临床期DN组(CDN组)。入院后行左手无名指甲襞微循环检查,对各组患者进行甲襞微循环评分。结果 NDR组、NPDR组、PDR组甲襞微循环总积分分别为(5.09±1.38)、(5.54±1.30)、(6.14±1.52)分,PDR组总积分高于NPDR组,NPDR组总积分高于NDR组(P均0.05)。NDN组、EDN组、CDN组甲襞微循环总积分分别为(5.14±1.32)、(5.64±1.35)、(6.38±1.32)分,CDN组总积分高于EDN组,EDN组总积分高于NDN组(P均0.05)。结论 2型糖尿病患者存在不同程度的甲襞微循环障碍,DR、DN患者的甲襞微循环障碍程度均重于单纯糖尿病患者。
[Abstract]:Objective to study the change and significance of nail fold microcirculation integral in type 2 diabetic microvascular disease. Methods 353 patients with type 2 diabetes mellitus were selected. According to the presence of diabetic retinopathy, (DR) was divided into normal group (NDR group), non-proliferative DR group (NPDR group), proliferative DR group (PDR group), (DN) of diabetic nephropathy group (NDN group) and microalbuminuria group (NDN group). White urine group (EDN group), clinical stage DN group (CDN group). After admission, the left ring finger nail fold microcirculation examination and nail fold microcirculation score were performed. Results the total score of nailfold microcirculation in NDR group, NPDR group and PDR group were (5.09 卤1.38), (5.54 卤1.30), (6.14 卤1.52, respectively. The total score of PDR group was higher than that of NPDR group, and the total score of NPDR group was higher than that of NDR group (P 0.05). The total score of nail fold microcirculation in NDR group, EDN group and CDN group was (5.14 卤1.32), (5.64 卤1.35), (6.38 卤1.32), and the total score in CDN group was higher than that in EDN group. The total score of EDN group was higher than that of NDN group (P 0.05). Conclusion patients with type 2 diabetes have different degrees of nailfold microcirculation disorder. The degree of nailfold microcirculation disorder in DR,DN patients is more serious than that in simple diabetes patients.
【作者单位】：中国人民解放军空军总医院;
【分类号】：R587.2

【相似文献】