代谢综合征人群中医体质调查及个体化调养保健方案的疗效
发布时间：2018-10-29 10:26
【摘要】：目的对代谢综合征患者进行中医体质辨识,根据患者不同中医体质制定个体化调养保健方案进行干预并评价其疗效。方法在401医院体检中心进行体检的人群中,按纳入标准和排除标准选择代谢综合征患者共280例作为研究对象,为每位代谢综合征患者检测代谢综合征的西医指标包括体重指数、血压、空腹状态下的血甘油三酯、高密度脂蛋白胆固醇和血糖水平,并进行中医体质评定。将280例代谢综合征患者随机分为对照组和干预组,每组各140例患者。对照组患者根据各项指南用药原则合理服用降压、降糖、降脂药,不实施其他干预。干预组患者在根据各项指南用药原则合理服用降压、降糖、降脂药的基础上,根据每位患者的不同体质选择适合其体质的个体化调养保健方案,包括指导科学合理的饮食、行为引导、精神调摄、心理疏导、体育运动、环境起居、生活习惯和生活方式的干预、保健穴位、中药调理等多项综合性的保健指导。干预治疗6个月后,观察两组患者体重指数、血压、空腹状态下的血甘油三酯、高密度脂蛋白胆固醇和血糖水平的变化,以评价个体化调养保健方案的效果。结果280例代谢综合征患者经中医体质量表辨识,体质分布特征如下:痰湿质79例,气虚质66例,湿热质48例,阴虚质32例,血瘀质18例,阳虚质15例,气郁质11例,平和质9例,特禀质2例。两组患者治疗前的年龄、性别、体质类型无统计学差异(P0.05),两组患者治疗前的体重指数、血压、空腹状态下的血甘油三酯、高密度脂蛋白胆固醇和血糖水平无统计学差异(P0.05)。两组患者分别采用不同治疗方案进行干预,在干预6个月后,复查结果显示,与本组患者治疗前相比较,两组患者治疗后的体重指数、血压和血甘油三酯水平均降低(P0.05),血高密度脂蛋白胆固醇水平增高(P0.05)。干预组患者的空腹血糖水平较治疗前降低(P0.05),而对照组患者的空腹血糖水平较治疗前未见明显改变(P0.05)。两组患者的治疗结果组间比较显示,干预组患者治疗前、后的体重指数、血压、空腹状态下的血甘油三酯、高密度脂蛋白胆固醇和血糖水平各项指标变化情况均较对照组更显著(P0.05)。结论对该研究中的280例代谢综合征患者进行中医体质辨识,主要体质类型依次为痰湿质、气虚质、湿热质,其中以痰湿体质所占比例最多。本研究中对干预组患者实施针对不同体质的个体化调养保健方案,结合各项指南指导服用西医药物治疗,而对照组仅在各项指南指导下服用西医药物治疗。两组患者分别治疗6个月后,干预组患者的体重指数、血压、空腹状态下的血甘油三酯、高密度脂蛋白胆固醇和血糖各项指标的均较对照组改善更显著,说明根据不同中医体质类型制定的个体化调养保健方案对代谢综合征的治疗切实有效。这体现了中西医结合的治疗特色和优势。
[Abstract]:Objective to identify the physique of the patients with metabolic syndrome (MS), and to make the individual health care program according to the different constitution of TCM and evaluate the curative effect. Methods A total of 280 patients with metabolic syndrome were selected according to inclusion criteria and exclusion criteria. Western medicine indexes including body mass index (BMI) were measured for each patient with metabolic syndrome. Blood pressure, fasting serum triglyceride, high density lipoprotein cholesterol and blood glucose levels, and Chinese medicine constitution evaluation. 280 patients with metabolic syndrome were randomly divided into control group and intervention group with 140 patients in each group. The patients in the control group took antihypertensive, hypoglycemic and lipid-lowering drugs according to the guidelines. On the basis of rational taking of antihypertensive, hypoglycemic and lipid-lowering drugs in accordance with the principles of drug use in the intervention group, the patients in the intervention group selected individual health care programs suitable for their physique according to the different physique of each patient, including guiding a scientific and reasonable diet. Behavioral guidance, mental adjustment, psychological guidance, sports, environmental living, living habits and lifestyle intervention, health care acupoints, traditional Chinese medicine, and other comprehensive health care guidance. After 6 months of intervention, the changes of body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose were observed in order to evaluate the effect of individualized regimen. Results the physical distribution characteristics of 280 patients with metabolic syndrome were as follows: phlegm dampness 79 cases, qi deficiency 66 cases, dampness and heat 48 cases, yin deficiency 32 cases, blood stasis 18 cases, yang deficiency 15 cases, qi stagnation 11 cases. There were 9 cases of pacification and 2 cases of special nature. There was no significant difference in age, sex and physical type between the two groups before treatment (P0.05). The body mass index (BMI), blood pressure (BP), triglyceride (triglyceride) in fasting state were not significantly different between the two groups before treatment (P0.05). There was no significant difference in high density lipoprotein cholesterol and blood glucose levels (P0.05). After 6 months of intervention, the results showed that the body mass index (BMI) of the two groups was higher than that of the patients before treatment. Blood pressure and serum triglyceride level were decreased (P0.05), blood high density lipoprotein cholesterol level increased (P0.05). The fasting blood glucose level in the intervention group was lower than that before treatment (P0.05), while the fasting blood glucose level in the control group was not significantly changed compared with that before treatment (P0.05). A comparison between the two groups showed that the body mass index (BMI), blood pressure (BP), serum triglyceride (TG) in fasting state were measured before and after treatment in the intervention group. The changes of high density lipoprotein cholesterol and blood glucose levels were more significant than those of the control group (P0.05). Conclusion 280 cases of metabolic syndrome in this study were identified by TCM physique. The main physique types were phlegm dampness, qi deficiency, dampness and heat, among which phlegm and dampness constitution accounted for the most. In this study, the patients in the intervention group were given individualized health care program for different physique, combined with the guidelines to guide the treatment of western medicine, while the control group only took western medicine under the guidance of various guidelines. After 6 months of treatment, the body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose in the intervention group were significantly improved than those in the control group. The results showed that the individualized regimen was effective in the treatment of metabolic syndrome according to different physique types of traditional Chinese medicine. This reflects the treatment characteristics and advantages of integrated Chinese and western medicine.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R589
本文编号：2297431
[Abstract]:Objective to identify the physique of the patients with metabolic syndrome (MS), and to make the individual health care program according to the different constitution of TCM and evaluate the curative effect. Methods A total of 280 patients with metabolic syndrome were selected according to inclusion criteria and exclusion criteria. Western medicine indexes including body mass index (BMI) were measured for each patient with metabolic syndrome. Blood pressure, fasting serum triglyceride, high density lipoprotein cholesterol and blood glucose levels, and Chinese medicine constitution evaluation. 280 patients with metabolic syndrome were randomly divided into control group and intervention group with 140 patients in each group. The patients in the control group took antihypertensive, hypoglycemic and lipid-lowering drugs according to the guidelines. On the basis of rational taking of antihypertensive, hypoglycemic and lipid-lowering drugs in accordance with the principles of drug use in the intervention group, the patients in the intervention group selected individual health care programs suitable for their physique according to the different physique of each patient, including guiding a scientific and reasonable diet. Behavioral guidance, mental adjustment, psychological guidance, sports, environmental living, living habits and lifestyle intervention, health care acupoints, traditional Chinese medicine, and other comprehensive health care guidance. After 6 months of intervention, the changes of body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose were observed in order to evaluate the effect of individualized regimen. Results the physical distribution characteristics of 280 patients with metabolic syndrome were as follows: phlegm dampness 79 cases, qi deficiency 66 cases, dampness and heat 48 cases, yin deficiency 32 cases, blood stasis 18 cases, yang deficiency 15 cases, qi stagnation 11 cases. There were 9 cases of pacification and 2 cases of special nature. There was no significant difference in age, sex and physical type between the two groups before treatment (P0.05). The body mass index (BMI), blood pressure (BP), triglyceride (triglyceride) in fasting state were not significantly different between the two groups before treatment (P0.05). There was no significant difference in high density lipoprotein cholesterol and blood glucose levels (P0.05). After 6 months of intervention, the results showed that the body mass index (BMI) of the two groups was higher than that of the patients before treatment. Blood pressure and serum triglyceride level were decreased (P0.05), blood high density lipoprotein cholesterol level increased (P0.05). The fasting blood glucose level in the intervention group was lower than that before treatment (P0.05), while the fasting blood glucose level in the control group was not significantly changed compared with that before treatment (P0.05). A comparison between the two groups showed that the body mass index (BMI), blood pressure (BP), serum triglyceride (TG) in fasting state were measured before and after treatment in the intervention group. The changes of high density lipoprotein cholesterol and blood glucose levels were more significant than those of the control group (P0.05). Conclusion 280 cases of metabolic syndrome in this study were identified by TCM physique. The main physique types were phlegm dampness, qi deficiency, dampness and heat, among which phlegm and dampness constitution accounted for the most. In this study, the patients in the intervention group were given individualized health care program for different physique, combined with the guidelines to guide the treatment of western medicine, while the control group only took western medicine under the guidance of various guidelines. After 6 months of treatment, the body mass index, blood pressure, serum triglyceride, high density lipoprotein cholesterol and blood glucose in the intervention group were significantly improved than those in the control group. The results showed that the individualized regimen was effective in the treatment of metabolic syndrome according to different physique types of traditional Chinese medicine. This reflects the treatment characteristics and advantages of integrated Chinese and western medicine.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R589
【参考文献】
相关期刊论文 前1条
1 潘玲,冯全生;八味丸方药对代谢综合征患者治疗效应的临床观察[J];四川生理科学杂志;2005年02期
，本文编号：2297431
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