急诊严重高钠血症患者的临床症状及病死率相关因素分析

发布时间：2018-11-05 10:19

【摘要】：目的探讨急诊科就诊高钠血症患者的一般临床特征、症状与病死率的关系。方法对2014年4月到2016年4月到郑州大学附属洛阳中心医院急诊科就诊的高钠血症患者进行了回顾性分析。239例患者血钠离子(Na~+)145mmol/L,平均年龄(65.13±12.14)岁,平均Na~+水平为(157.71±9.42)mmol/L;根据血Na~+水平分为血Na~+145~160mmol/L组与血Na~+≥160mmol/L组;比较两组患者的一般临床特征、症状、疾病及病死率。结果血Na~+≥160mmol/L组老年痴呆症发病率较血Na~+145~160mmol/L高(P=0.012),血肌酐、氯离子(Cl-)、血浆渗透压水平均较高(P=0.014,P=0.001,P=0.004);血Na~+≥160mmol/L组患者的平均动脉压(MAP)和格拉斯哥昏迷评分(GCS)较血Na~+145~160mmol/L组低(P=0.001,P=0.000),脉搏较快(P=0.000);血Na~+≥160mmol/L组低血压、气促、消化道出血和神经精神症状发生率较血Na~+145~160mmol/L组高(P0.01),脱水、肺炎、尿路感染的发病率较血Na~+145~160mmol/L组高(P0.01);Na~+≥160mmol/L组病死率明显高于Na~+145~160mmol/L组(P=0.000)。多因素Logistic回归分析显示,低血压、发热、气促、消化道出血及神经精神症状与高钠血症患者病死率有相关性。结论严重高钠血症患者病死率较高,如患者合并低血压、发热、气促、消化道出血及神经精神症状等症状,临床医生需高度警惕,积极救治,尽力降低病死率。
[Abstract]:Objective to investigate the general clinical features, the relationship between symptoms and mortality of patients with hypernatremia in emergency department. Methods from April 2014 to April 2016, the patients with hypernatremia in the emergency department of Luoyang Central Hospital affiliated to Zhengzhou University were retrospectively analyzed. The average age was (65.13 卤12.14) years old, the average age was (65.13 卤12.14) years, and the serum sodium ion (Na~) was 145 mmol / L in 239 patients. The average Na~ level was (157.71 卤9.42) mmol/L;. According to the level of blood Na~, the patients were divided into two groups: blood Na~ 145~160mmol/L group and blood Na~ 鈮，

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