应用状态医学方法治疗2型糖尿病的临床观察

发布时间：2018-12-21 15:28

【摘要】：目的：本研究应用状态医学的方法,评估2型糖尿病患者临床状态,给予中西医治疗及心理干预,通过调整患者临床状态,希望能达到更好地控制血糖,并能恢复患者良好的心理健康水平与社会功能的目的,为临床治疗糖尿病提供新的思路与方法。方法：将66例符合标准的2型糖尿病患者,随机分为西药对照组及状态医学试验组,脱落3例,最后纳入统计33例,对照组31例,采用西药基础降糖药物治疗；试验组32例,在对照组的基础上,加用中药治疗及心理治疗。观察时间为3个月,分别于入组前、2周后、3个月后评估血糖指标(空腹血糖、餐后2h血糖、糖化血红蛋白)、宗氏抑郁自评量表(SDS)、宗氏焦虑自评量表(SAS)、糖尿病人生存质量特异性量表(DSQL)、中华健康状况量表(TCM-HSS)的得分变化。结果：运用状态医学方法的试验组取得良好的效果：1.在血糖指标控制方面,两组的空腹血糖(FBG)、餐后2h血糖(PBG)、糖化血红蛋白(HbAlc)的改善情况均明显好于治疗前(P0.05),但试验组治疗效果明显好于对照组,差异具有统计学意义(P0.05)。2.心理量表方面,试验组SAS与SDS量表得分显著低于治疗前(P0.01),且明显低于对照组得分(P0.01)。3.在生存质量改善方面,试验组在身体、心理、社会、治疗以及总评分5个维度得分比治疗前都有明显降低(P0.05)且优于对照组,具有统计学意义(P0.01),对照组仅在身体维度比治疗前得分明显降低(P0.05)。4.在中医症状疗效比较方面,试验组在精力、疼痛、大便、睡眠、体质、情绪及健康自评等方面得分比治疗前都有明显降低(P0.05),且上述6个方面(除疼痛项目)治疗后得分低于对照组(P0.05)。结论：运用状态医学方法能使2型糖尿病病人的血糖情况得到有效控制,且能较好改善抑郁、焦虑症状,提高生活质量,是治疗2型糖尿病的有效方法,具有推广价值。
[Abstract]:Objective: to evaluate the clinical status of patients with type 2 diabetes mellitus by using the method of state medicine, and to give traditional Chinese and western medicine treatment and psychological intervention, in order to control blood glucose better by adjusting the clinical status of patients. It can restore the good mental health level and social function of the patients and provide new ideas and methods for the clinical treatment of diabetes mellitus. Methods: 66 patients with type 2 diabetes were randomly divided into western medicine control group and state medicine trial group. 33 cases were included in statistics and 31 cases in control group. Experimental group 32 cases, on the basis of the control group, plus Chinese medicine treatment and psychological treatment. The blood glucose index (fasting blood glucose, postprandial 2 h blood glucose, glycosylated hemoglobin) and the Zong's depression self-rating scale (SDS), the Zongs anxiety scale (SAS),) were evaluated before, 2 weeks and 3 months respectively Changes of (DSQL), Chinese Health status scale (TCM-HSS) in Diabetic patients with quality of Life (QOL). Results: the experimental group using state medicine method achieved good results: 1. In the control of blood glucose index, the improvement of (PBG), glycosylated hemoglobin (HbAlc) at 2h postprandial blood glucose of (FBG), in both groups was better than that before treatment (P0.05), but the effect of treatment in the experimental group was better than that in the control group. The difference was statistically significant (P0.05). The scores of SAS and SDS in the test group were significantly lower than those before treatment (P0.01) and significantly lower than those in the control group (P0.01). In terms of improving quality of life, the scores of five dimensions of body, psychology, society, treatment and total score in the experimental group were significantly lower than those before treatment (P0.05) and better than that in the control group (P0.01). The control group only in the body dimension than before treatment scores significantly decreased (P0.05). The scores of energy, pain, defecation, sleep, physique, mood and health self-evaluation in the experimental group were significantly lower than those before treatment (P0.05). The scores of the above 6 aspects (except pain items) after treatment were lower than those in the control group (P0.05). Conclusion: the application of state medicine can effectively control the blood glucose of type 2 diabetic patients, and can improve the depression, anxiety and quality of life. It is an effective method for the treatment of type 2 diabetes, and it is worth popularizing.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R587.1

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