社区老年人高尿酸血症患病率及危险因素调查研究

发布时间：2018-12-26 11:50

【摘要】：目的调查广州社区老年人尿酸(UA)水平、高尿酸血症(HUA)患病率及危险因素,为预防HUA提供依据。方法收集1 409例65岁以上老年人的血压(BP)、空腹血糖(FPG)、血UA、肌酐(Cr)、三酰甘油(TG)、总胆固醇(TC)、高密度及低密度脂蛋白胆固醇(HDL-C,LDL-C)等指标,进行年龄分层,Logistic回归模型分析HUA危险因素。结果HUA患病率为37.8%,男性为24.6%,女性为50.2%。男女UA水平及HUA患病率随年龄而增高。HUA的危险因素有年龄、性别、吸烟、Cr、TG、LDL-C、收缩压、高血压、高TG症、高LDL-C血症,保护因素有HDL-C。结论应警惕HUA的危险因素,并做出针对性的预防措施,才能获得良好的预防效果。
[Abstract]:Objective to investigate the level of uric acid (UA), prevalence and risk factors of hyperuricemia (HUA) in the elderly in Guangzhou community, and to provide evidence for the prevention of HUA. Methods Serum UA, creatinine, (Cr), triglyceride, total cholesterol, (TC), high density lipoprotein cholesterol (HDL-C,) and low density lipoprotein cholesterol (HDL-C,) were collected from 1 409 patients over 65 years old. Blood pressure, (BP), fasting blood glucose, (FPG),. LDL-C, age stratification and Logistic regression model were used to analyze the risk factors of HUA. Results the prevalence of HUA was 37.8%, 24.6% in males and 50.2% in females. The risk factors of HUA are age, sex, smoking, Cr,TG,LDL-C, systolic blood pressure, hypertension, hyperTG, hyperLDL-C and HDL-C.. Conclusion the risk factors of HUA should be alert and preventive measures should be taken in order to obtain good preventive effect.
【作者单位】：陕西中医药大学附属医院脑病科;广东省中医院张学文学术经验传承工作室;
【基金】：国家自然科学基金资助项目(81173256) 广东省自然科学基金资助项目(S2011010005984)
【分类号】：R589.7

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