广州天河社区绝经后妇女血清25羟维生素D水平与骨密度的相关性分析

发布时间：2018-12-30 12:16

【摘要】：目的调查广州天河区绝经后妇女维生素D水平及其与骨密度的关系。方法随机选取2015年4月至2015年8月在广州市天河区前进街社区卫生服务中心体检的109名绝经后妇女,年龄49~75岁。检测血清25(OH)D水平,分析血清25(OH)D水平与骨转换指标和骨密度(BMD)的相关性。结果 25.7%的受试者血清25(OH)D水平≥75 nmol/L,41.3%在50~75 nmol/L之间,33.0%低于50 nmol/L。双变量分析显示血清25(OH)D水平与血清PINP、β-CTX水平无相关性。股骨颈BMD与血清25(OH)D正相关(r=0.373,P=0.030),校正年龄和体重指数(BMI)后,相关性仍存在(r=0.174,P=0.049)。多元回归分析显示年龄、BMI、25(OH)D是股骨颈BMD的预测因子(R2=0.325)。结论绝经后女性广泛存在血清25(OH)D不足或缺乏,血清25(OH)D水平与股骨颈BMD正相关,适当补充维生素D对维持股骨颈区域的骨量至关重要。
[Abstract]:Objective to investigate the relationship between vitamin D level and bone mineral density (BMD) in postmenopausal women in Tianhe District, Guangzhou. Methods A total of 109 postmenopausal women aged 4975 years were randomly selected from April 2015 to August 2015 in Qianjie Community Health Service Center, Tianhe District, Guangzhou. The serum 25 (OH) D level was measured and the correlation between serum 25 (OH) D level and bone turnover index and bone mineral density (BMD) was analyzed. Results the serum 25 (OH) D level 鈮，

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