不同运动方式对2型糖尿病患者脂肪代谢率的影响

发布时间：2019-02-16 21:06

【摘要】：目的：观察两种不同的运动方式(平板运动和功率自行车运动)对2型糖尿病患者脂肪代谢率的影响。方法：选取20名2014.10-2014.12期间在东南大学附属中大医院内分泌科住院的2型糖尿病患者进行心肺运动试验,随机化选择平板或功率车运动形式,分别进行两种运动,使用气体代谢分析仪(k4b2)帮助制定等强度等运动时间的运动方案,采集运动中摄氧量、二氧化碳排出量、心率及血压等指标,监测运动前后血糖变化,并计算不同运动方式下的脂肪氧化率。计量资料数据以均数±标准差(x±s)表示,均数间两两比较根据实际情况采用配对样本t检验,变量之间的相关性采用pearson相关系数进行比较,应用SPASS18.0统计软件分析数据,P0.05认为差异具有统计学意义。结果：1、受试者无论进行平板运动还是功率自行车运动,运动后的血糖均显著下降(p0.001)；2、相同强度相同时间不同运动方式下,功率自行车的运动中靶心率、RPP、PRE、VE/VO2及RQ均高于平板运动(p=0.008、p=0.031、p=0.030、p0.001及p=0.002),而平板运动的VO2、VO2/kg、脂肪氧化率和每公斤体重脂肪氧化率则明显高于功率白行车(p0.001、p--0.004、p0.001及p0.001),其他指标如血糖、血糖差、血压、血压差及其他气体代谢指标等则均无明显统计学差异；3、无论是体重正常或是超重的受试者,其平板运动的脂肪氧化率及每公斤体重脂肪氧化率均明显高于功率自行车,差异有统计学意义(p0.05)；而无论进行平板运动或是功率自行车运动,体重正常和超重的受试者其脂肪氧化率和每公斤体重脂肪氧化率均无明显差异(p0.05)；4、无论进行平板运动或是功率自行车运动,受试者的体重、BMI、腰围、臀围和腰臀比的变化与其脂肪氧化率的变化均无明显一致性,pearson系数0.2,呈极弱相关或无相关。结论：1、在等强度等运动时间条件下,不同运动方式的降糖效果相似,提示运动方式并不是糖尿病患者血糖控制的决定因素;2、在等强度等运动时间条件下,2型糖尿病患者的体重、BMI、腰围、臀围和腰臀比的变化与其脂肪氧化率的变化均无明显一致性,提示2型糖尿病患者的体型与其运动时的脂肪氧化率无关；3、在等强度等运动时间条件下,2型糖尿病患者进行功率自行车运动的运动中靶心率及劳累程度大于平板运动,而脂肪氧化率却明显小于平板运动,提示2型糖尿病患者在进行运动疗法时,平板运动方式可能更轻松,也更利于患者的脂肪代谢,增强减脂效果,但相关机制还需进一步研究。
[Abstract]:Aim: to observe the effects of two different exercise patterns (treadmill exercise and bicycle exercise) on fat metabolism in patients with type 2 diabetes mellitus. Methods: a cardiopulmonary exercise test was conducted in 20 patients with type 2 diabetes mellitus hospitalized in the Department of Endocrinology, affiliated Chinese University Hospital of Southeast University during the period from October to December 2014. Gas Metabolism Analyzer (k4b2) was used to work out the exercise plan of equal intensity and exercise time. The indexes of oxygen intake, carbon dioxide output, heart rate and blood pressure were collected to monitor the changes of blood glucose before and after exercise. The oxidation rate of fat was calculated under different exercise modes. The measurement data are expressed as mean 卤standard deviation (x 卤s). According to the actual situation, the paired sample t test is used to compare the mean and the correlation between variables is compared by pearson correlation coefficient, and the data are analyzed by SPASS18.0 software. P0.05 that the difference was statistically significant. Results: 1, the blood glucose of the subjects decreased significantly after exercise (p0.001), regardless of the treadmill exercise or the bicycling exercise. 2. Under the same intensity, same time and different exercise mode, the target center rate, RPP,PRE,VE/VO2 and RQ of the bicycle were higher than that of the plate exercise (p0.008 / 0. 031 / 0. 030p0. 001 and p0. 002), while the VO2, of the treadmill exercise was higher than that of the treadmill exercise. VO2/kg, fat oxidation rate and fat oxidation rate per kilogram of body weight were significantly higher than that of power white car (p0.001p 0.004cp0.001 and p0.001), other indicators such as blood sugar, blood glucose, blood pressure, There was no significant difference in blood pressure difference and other gas metabolism indexes. (3) the fat oxidation rate and fat oxidation rate per kilogram of body weight of healthy or overweight subjects were significantly higher than those of bicycle (p0.05). However, there was no significant difference between normal and overweight subjects in fat oxidation rate and fat oxidation rate per kilogram of body weight (p0.05). (4) the changes of body weight, BMI, waist circumference, hip circumference and waist-to-hip ratio were not significantly consistent with the changes of fat oxidation rate, but the pearson coefficient was 0.2, which was weakly correlated with or without correlation between body weight, BMI, waist circumference and waist-to-hip ratio. Conclusion: 1 under the condition of equal intensity and exercise time, the hypoglycemic effect of different exercise modes is similar, suggesting that exercise mode is not the decisive factor of blood glucose control in diabetic patients; 2. The changes of body weight, BMI, waist circumference, hip circumference and waist-to-hip ratio in type 2 diabetic patients were not significantly consistent with the changes of fat oxidation rate under the condition of equal intensity and exercise time. It is suggested that the type of type 2 diabetes is not related to the oxidation rate of fat during exercise. 3. Under the condition of equal intensity and time of exercise, the target heart rate and tiredness of type 2 diabetic patients were higher than that of treadmill exercise, but the oxidation rate of fat was obviously lower than that of treadmill exercise. The results suggest that the treadmill exercise may be more relaxed and beneficial to the fat metabolism of patients with type 2 diabetes mellitus, but the related mechanism needs further study.
【学位授予单位】：东南大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R587.1

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