跌倒与双足静力性平衡及羧化不全骨钙素水平的相关性分析

发布时间：2019-02-23 12:23

【摘要】：目的探讨老年人跌倒与双足静力性平衡及羧化不全骨钙素(uc OC)水平的关系。方法收集我院2016年10月至2017年1月查体中心健康查体的125例健康老年人(1年内无跌倒史的31例、1次跌倒史的31例、2次跌倒史的30例、3次及更多跌倒史的33例)进行研究,使用酶联免疫吸附法(ELISA)测定血清uc OC水平,应用Footscan Balance 7.7平板式足底压力测试系统检测受试者双足静止站立时压力中心(center of pressure,COP)的移动轨迹,以及包绕压力中心移动轨迹的椭圆面积(95%confidence ellipse area,EA),评价静力性平衡能力,各组之间进行比较。结果各组受试者在年龄、性别、体重指数、腰臀比等方面差异均无统计学意义(P0.05),老年人跌倒组较对照组,Cop X,Cop Y均无明显差异,跌倒组较对照组压力中心移动总长度TTW、包绕95%压力中心移动轨迹在内的椭圆面积(EA)差异有统计学意义(P0.05),同时跌倒组较对照组羧化不全骨钙素升高,差异具有统计学意义(P0.05)。结论老年人跌倒次数与静力性平衡能力呈负相关,且与羧化不全骨钙素水平呈正相关。
[Abstract]:Objective to investigate the relationship between fall, static balance and carboxylation of osteocalcin (uc OC) in the elderly. Methods from October 2016 to January 2017, 125 healthy elderly patients (31 cases with no history of fall, 31 cases with history of once fall, 30 cases with history of two falls) were collected from the health examination center of our hospital from October 2016 to January 2017. The serum uc OC level was measured by enzyme linked immunosorbent assay (ELISA), and the pressure center (center of pressure, was measured by Footscan Balance 7.7 flat plantar pressure test system. COP), and the elliptical area (95%confidence ellipse area,EA) of the orbit around the pressure center, to evaluate the static balance ability, and to compare the two groups. Results there was no significant difference in age, sex, body mass index, waist-to-hip ratio between the three groups (P0.05), but there was no significant difference in Cop XCop Y between the elderly group and the control group. Compared with the control group, there was a significant difference in (EA) in the elliptical area including the total length of the pressure center moving TTW, around 95% of the pressure center in the fall group (P0.05), and the increase of the carboxylation incomplete osteocalcin in the fall group compared with the control group (P0.05). The difference was statistically significant (P0.05). Conclusion the number of falls in the elderly is negatively correlated with the static balance ability and positively correlated with the level of carboxylated incomplete osteocalcin.
【作者单位】：青岛大学附属医院黄岛院区内分泌科;山东省高密市中医院内分泌科;青岛大学附属医院黄岛院区检验科;
【分类号】：R592

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