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2型糖尿病患者血清维生素D水平及其影响因素

发布时间:2019-04-01 20:55
【摘要】:目的评估2型糖尿病患者血清25-羟维生素D3[25(OH)D3]水平与代谢的关系。方法选择2014年6月至2015年6月于我院内分泌科住院的辽宁省地区2型糖尿病患者254例,根据血清25(OH)D3测定时间将所有患者分为A组(1~5月和12月)和B组(6~11月),比较2组25(OH)D3、糖化血红蛋白、空腹血糖等代谢指标,另外根据血清25(OH)D3水平将A、B 2组各分为4个亚组:A1组和B1组,25(OH)D3≥30 ng/m L;A2组和B2组,25(OH)D3为20~30 ng/m L;A3组和B3组,25(OH)D3为10~20ng/m L;A4组和B4组,25(OH)D310 ng/m L。比较各亚组相关代谢指标。结果 B组血清25(OH)D3水平高于A组(P0.001)。A3组糖化血红蛋白低于A4组(P=0.043)。A组和B组以及各个亚组间血钙差异无统计学意义(P0.05)。结论辽宁省地区的2型糖尿病患者维生素D水平普遍较低,冬春季较夏秋季更显著。辽宁省地区2型糖尿病患者需要补充维生素D,增加户外运动。2型糖尿病患者维生素D缺乏与血糖水平有关。血清钙不能作为评估维生素D的指标。
[Abstract]:Objective to evaluate the relationship between serum 25-hydroxyvitamin D _ 3 [25 (OH) D _ 3] and metabolism in patients with type 2 diabetes mellitus. Methods from June 2014 to June 2015, 254 patients with type 2 diabetes mellitus in Liaoning province were divided into two groups: group A (1 ~ 5 months and 12 months) and group B (6 ~ 11 months) according to the time of serum 25 (OH) D3 determination. The metabolic indexes such as 25 (OH) D 3, glycosylated hemoglobin and fasting blood glucose were compared between the two groups. In addition, A and B 2 groups were divided into four subgroups according to the level of serum 25 (OH) D3: group A1 and group B1, 25 (OH) D3 鈮,

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